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Exercise Training for Heart Failure
N/A
Recruiting
Led By Kanokwan Bunsawat, PhD
Research Sponsored by VA Office of Research and Development
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
New York Heart Association (NYHA) functional class II or III
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up change from baseline skeletal muscle blood flow at 8 weeks
Awards & highlights
Study Summary
This trial will study how well exercise training can improve symptoms and quality of life in patients with heart failure with preserved ejection.
Who is the study for?
This trial is for adults with heart failure who can consent, have a specific type of heart failure (HFpEF) where the heart pumps well but is stiff, and show certain blood markers. It's not for those with severe heart issues, orthopedic limits that prevent exercise, women on hormone therapy, smokers, or pregnant women.Check my eligibility
What is being tested?
The study looks at how well patients with HFpEF respond to an 8-week exercise program compared to healthy people. The focus is on understanding why these patients struggle with exercise by measuring changes in muscle blood flow.See study design
What are the potential side effects?
Since the intervention involves exercise training rather than medication, side effects may include typical post-exercise symptoms like muscle soreness or fatigue. However, risks are generally low and will be monitored.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
My heart condition limits my physical activity but I can still perform light tasks.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ change from baseline six-minute walk test distance at 8 weeks
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~change from baseline six-minute walk test distance at 8 weeks
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Muscle blood flow
Six-minute walk test
Trial Design
1Treatment groups
Experimental Treatment
Group I: Exercise trainingExperimental Treatment1 Intervention
Patients with HFpEF will participate in the 8 weeks of supervised, two-legged, knee extensor exercise training for 3 days per week. Each exercise session will involve a 5-min warm-up and a 5-min cool-down, and exercise intensity will range between 40%-90% of maximal work rate. Maximal work rate will be re-assessed every two weeks.
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Who is running the clinical trial?
VA Office of Research and DevelopmentLead Sponsor
1,606 Previous Clinical Trials
3,305,970 Total Patients Enrolled
39 Trials studying Heart Failure
63,188 Patients Enrolled for Heart Failure
Kanokwan Bunsawat, PhDPrincipal InvestigatorVA Salt Lake City Health Care System, Salt Lake City, UT
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- My heart failure is severe and cannot be managed with medication.My heart failure is not due to a major untreated valve problem, except for a specific type of leaky heart valve caused by heart muscle weakness.I am 18 or older and can sign a consent form.I have a heart condition such as acute coronary syndrome, infiltrative cardiomyopathy, or myocarditis.I am not pregnant and unlikely to become pregnant, as I am postmenopausal.My heart condition limits my physical activity but I can still perform light tasks.I am not currently on hormone replacement therapy.I cannot do exercises that require straightening my knee due to physical limitations.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Research Study Groups:
This trial has the following groups:- Group 1: Exercise training
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
How many individuals are being included in this research endeavor?
"Affirmative, the information on clinicaltrials.gov shows this trial is actively recruiting participants. This medical study was posted July 1st 2022 and has been edited up until July 15th 2022. Presently, 35 patients are needed for enrollment at one site."
Answered by AI
Are there any available participant positions in the current clinical trial?
"Affirmative. Clinicaltrials.gov's data reveals that this clinical trial, which was initiated on July 1st 2022 and last revised on the 15th of July, is actively recruiting 35 individuals from a single location."
Answered by AI
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