Remote Enhance Fitness for Malignancies

1
Effectiveness
1
Safety
University of Vermont, Burlington, VT
Remote Enhance Fitness - Behavioral
Eligibility
18+
All Sexes
Eligible conditions
Malignancies

Study Summary

This study is evaluating whether an online exercise program can help older cancer survivors.

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Treatment Effectiveness

Effectiveness Estimate

1 of 3

Study Objectives

This trial is evaluating whether Remote Enhance Fitness will improve 4 primary outcomes and 6 secondary outcomes in patients with Malignancies. Measurement will happen over the course of 4 months.

4 months
30 second-sit-to-stand test
Adapted Technology Acceptance Model Scale
Duke Activity Status Index
Fatigue
Five time sit-to-stand test
Four-stage balance test
Patient Reported Outcome Measurement System (PROMIS)-Physical Function10a
Physical Activity (PA) and Sedentary Time Assessment
Sleep disturbance
Technology Use and Acceptance

Trial Safety

Trial Design

2 Treatment Groups

Control
Intervention Group - Remote Enhance Fitness

This trial requires 39 total participants across 2 different treatment groups

This trial involves 2 different treatments. Remote Enhance Fitness is the primary treatment being studied. Participants will all receive the same treatment. There is no placebo group. The treatments being tested are not being studied for commercial purposes.

Intervention Group - Remote Enhance Fitness
Behavioral
Participants assigned to the intervention group will participated in a 16-week remote exercise intervention. Following a home/space environment and technology needs assessment, participants will attend a one-on-one orientation and practice class with a research assistant. Participants will join a live-streamed, instructor-led group Enhance Fitness exercise session for 1-hour, 3 days/week for 4 months (16-weeks).
ControlNo treatment in the control group

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: 4 months
This trial has the following approximate timeline: 3 weeks for initial screening, variable treatment timelines, and roughly 4 months for reporting.

Who is running the study

Principal Investigator
N. G.
Prof. Nancy Gell, Associate Professor
University of Vermont

Closest Location

University of Vermont - Burlington, VT

Eligibility Criteria

This trial is for patients born any sex aged 18 and older. There are 7 eligibility criteria to participate in this trial as listed below.

Mark “yes” if the following statements are true for you:
Rural residence by self-report and confirmed with Rural-Urban Commuting Area Codes
Stage I-III cancer history
Completion of adjuvant chemotherapy, radiation therapy, or surgery for cancer diagnosis
Age 60 years or older
Ability to walk for exercise
Self-reported minimal or inconsistent participation in strengthening exercise and physical activity (< 150 minutes/week moderate-to-vigorous physical activity; confirmed with baseline accelerometer measures)
Clearance for exercise based on a modified, combined Screening Cancer Survivors for Unsupervised Moderate-to-Vigorous Intensity Exercise and the Screening for Physical Activity Readiness Questionnaire (PAR-Q) or physician approval as needed based on the pre-screening/PAR-Q responses

Patient Q&A Section

Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What is malignancies?

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According to current evidence, cancer is a complex condition that involves the development and progression of cancer cells in the body by genetic or environmental factors. The most common kinds of cancer are skin cancer, lymphoma, cervical cancer, lung cancer, and testicular cancer. The most curative treatment for cancer is surgery, although it is possible to prevent cancer progression through medical interventions. In general, the better you know your cancer, the better you will be able to treat it. It is important that the relevant oncologist be consulted and treatment plans developed before the operation.

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What causes malignancies?

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Infections, environmental chemicals and genetics.\n\nThe following diseases are a few of those that may occur at a very high rate in people with AHD. This list is not complete, and many other diseases are either very rare in the general population or have not yet been fully researched in the AHD community.

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How many people get malignancies a year in the United States?

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In this country malignancies are the most common reason for hospital admissions. The incidence of cancer increased from 1950 to 1987. More than 75% of cancer cases are related to smoking and alcohol abuse. The increasing incidence of cancer, the role of risk factors in the etiology of cancer, and the differences between incidence, incidence and distribution of cancer within countries should be a matter of importance in medical research.

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Can malignancies be cured?

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This report establishes the feasibility of using non-myeloablative treatments to achieve complete disease control when applicable. However, patients with malignant neoplasms who succumb to treatment are seldom cured from the disease.

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What are common treatments for malignancies?

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Many patients with malignancies receive medications, such as anti-tumor cytotoxics, alkylating agents, and antimetabolite agents, and other agents like antihistamines or antispasmodics. Radiotherapy is a standard therapeutic option for many patients with tumors. Surgery may be required in some cases and is used in other cases involving tumors or growths of the skin.

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What are the signs of malignancies?

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Tumor markers are important in the management of malignancy. Their determination helps to identify the tumour and aids in the early diagnosis and management of malignancy. They are of particular importance in the management of Hodgkin's disease and non-Hodgkin's lymphoma, malignant pleural mesothelioma, and breast carcinoma. However, there is no conclusive pattern to which a particular tumor marker may be linked.

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Have there been other clinical trials involving remote enhance fitness?

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The REFEED trial is the first to demonstrate the potential to deliver improved health outcomes from a high-intensity exercise programme. This was achieved in a programme of moderate training intensity, but not in a higher intensity programme. Given the magnitude of the current obesity and diabetes risk, the positive effects of this intervention in overweight and obese men should encourage increased use of an exercise programme lasting longer than 8 weeks with more visits.

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Is remote enhance fitness safe for people?

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The combination of exercise with the use of remote technologies appear to be at least as safe as one-on-one supervised intervention in healthy adults, and warranting further evaluation in frail and older adults.

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How does remote enhance fitness work?

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The fitness training program with VR was positively received, and the improved outcomes in strength, flexibility, and aerobic fitness, suggest that the remote program with VR is effective and feasible for patients. Clinicians should consider the value of such interventions as fitness programs are essential for the promotion of quality of life and general health.

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Who should consider clinical trials for malignancies?

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[The elderly and those who are not white need to be considered in design of clinical trials for malignancy] The impact of these populations on trial design is largely unknown and may be underestimated.

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What is the latest research for malignancies?

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In general, the incidence of malignancies has increased in most countries in this period, whereas the incidence of many malignant diseases such as leukemia, [lung cancer](https://www.withpower.com/clinical-trials/lung-cancer), gallbladder cancers, and renal cancers have remained unchanged. The overall incidence of pancreatic cancer and liver cancer continues to rise in most countries. In men, the incidence is steady for esophageal carcinoma and breast cancer, while in women, the incidence remains stable for breast cancer but increases for cervical cancer.

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What does remote enhance fitness usually treat?

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This is one of the first studies to demonstrate that remoteness can be used to increase physical fitness and health in healthy participants. The study provides evidence that health interventions for remote enhanced fitness that target healthy behaviours are beneficial, and that this effect can persist. It also demonstrates the feasibility of undertaking such an intervention and supports the need to undertake randomized controlled trials evaluating the beneficial impact of remote enhanced fitness on health and quality of life. The research raises important issues for health promotion, exercise and sport practitioners and health policy and education designers.

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