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Rapamycin for Aging (PEARL Trial)
PEARL Trial Summary
This trial is testing whether a drug is safe and effective at reducing signs of aging in older adults.
PEARL Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2009 Phase 4 trial • 20 Patients • NCT00223678PEARL Trial Design
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Who is running the clinical trial?
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- People of any gender can participate.People of any race or ethnic background can participate.You are currently receiving or planning to receive chemotherapy or other cancer treatments.You have a chronic open wound or problems with healing wounds.You have Type I diabetes or Type II diabetes that requires insulin for treatment.You have struggled with drug or alcohol addiction that has not been treated or was treated within the last 5 years.You have fibromyalgia, chronic fatigue syndrome/myalgic encephalomyelitis, or breast implant illness.You have untreated or poorly controlled mental health conditions like PTSD, bipolar disorder, schizophrenia, or other mood disorders. You have also been hospitalized in the past for mental health reasons.You are not interested in trying Rapamycin for a purpose other than what it is approved for.
- Group 1: Rapamycin 10
- Group 2: Placebo 1
- Group 3: Rapamycin 5
- Approved for 5 Other Conditions - This treatment demonstrated efficacy for 5 other conditions.
- All Individual Drugs Already Approved - Therapies where all constituent drugs have already been approved are likely to have better-understood side effect profiles.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Is the age threshold for this clinical experiment limited to those over seventy-five years old?
"This clinical trial seeks patients that fulfill the criteria of being between 50 and 85 years old. On the other hand, there are 55 trials for people aged below 18 and 334 research studies available for those above 65."
Am I eligible to become involved in this research initiative?
"Qualified patients are aged between 50 and 85, with the trial looking to enrol approximately 150 applicants."
What conditions are typically addressed with Rapamycin?
"Rapamycin is a popular intervention for organ transplant rejection, liver disease, and kidney conditions such as renal angiomyolipomas."
How many participants have enrolled in the clinical trial?
"Unfortunately, this research study is not currently enrolling participants. It was initially posted on January 1st 2020 and last updated on October 3rd 2022. If you're looking for further studies, there are 245 medical trials related to aging that have open enrolment slots and 125 studies regarding Rapamycin which are actively searching for individuals."
Have any past investigations explored the efficacy of Rapamycin?
"At the moment, 125 trials are being administered for Rapamycin. 13 of those initiatives have reached Phase 3 development and many are based in Cincinnati, Ohio with a total of 1074 experiment sites across the world."
Is there room for additional participants in this experiment?
"At present, this clinical investigation is not enrolling new participants. It was initially listed on the 1st of January 2020 and last modified on October 3rd 2022. If you are seeking other studies to participate in, there are 245 trials related to aging that are actively recruiting as well as 125 for Rapamycin."
How hazardous can Rapamycin be for those receiving it as therapy?
"With respect to safety, rapamycin was rated a 2 on a scale of 1-3 since it is currently in the second phase of clinical trials and evidence has been collected that supports its security but not necessarily efficacy."
Who else is applying?
What state do they live in?
How old are they?
What site did they apply to?
What portion of applicants met pre-screening criteria?
How many prior treatments have patients received?
Why did patients apply to this trial?
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