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Opioid

PMD-200 NOL group for Anesthesia Awareness

Phase 3
Waitlist Available
Led By Kurt Ruetzler, MD
Research Sponsored by The Cleveland Clinic
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 60 minutes
Awards & highlights

Study Summary

This trial showed that using a computer to guide how much fentanyl is given to a patient during surgery results in better recovery characteristics afterwards.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~60 minutes
This trial's timeline: 3 weeks for screening, Varies for treatment, and 60 minutes for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Pain Scores
Secondary outcome measures
Pain Scores <5.

Trial Design

2Treatment groups
Active Control
Group I: PMD-200 NOL groupActive Control1 Intervention
Clinicians will titrate fentanyl to keep PMD-200 NOL under 25 - always using good clinical judgement for individual patients
Group II: Control GroupActive Control1 Intervention
Clinicians will be blinded to PMD-200 NOL monitoring and use clinical judgement to determine how much fentanyl should be given, and when.

Find a Location

Who is running the clinical trial?

The Cleveland ClinicLead Sponsor
1,027 Previous Clinical Trials
1,364,205 Total Patients Enrolled
Kurt Ruetzler, MDPrincipal InvestigatorThe Cleveland Clinic
3 Previous Clinical Trials
13,787 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are any of the participants in this trial over two decades old?

"This trial is for patients aged 21 to 85. If you are either under 18 or over 65, there may be other trials more suited for you as this clinical study has 10 and 38 active trials respectively in those age categories."

Answered by AI

What do doctors hope to learn from the Control Group in this clinical study?

"The Control Group is mostly used for the induction of anesthesia, but it has also been effective in treating high risk surgery, preanesthetic medication, and anesthetic premedication therapy."

Answered by AI

What are the risks associated with being in the Control Group for this study?

"The safety of the Control Group was rated 3 out of 3 by our team at Power. This is due to the fact that this is a Phase 3 trial, which means that there is both some data supporting efficacy and multiple rounds of data supporting safety."

Answered by AI

Who meets the requirements to participate in this experiment?

"The team conducting this study is currently recruiting 144 individuals that have had prior anesthesia and experienced negative side-effects. The ideal candidate also meets the following age and surgery criteria: 21-85 years old, major non-cardiac surgery lasting 2 or more hours."

Answered by AI

How many individuals are included in this research project?

"Unfortunately, this particular clinical trial is not currently looking for more participants. The study was first posted on December 30th 2020 and was last updated on March 7th 2022. There are other trials ongoing that might be of interest; 8 trials related to anesthesia and adverse effects as well as 48 control group studies are actively enrolling patients right now."

Answered by AI

Are people with the required medical conditions able to participate in this trial?

"Unfortunately, this particular trial is not seeking new patients at the moment. According to clinicaltrials.gov, it was initially posted on December 30th 2020 and updated for the last time on March 7th 2022. Although this study has stopped recruiting, there are 56 other ongoing trials that may be of interest."

Answered by AI
~17 spots leftby Apr 2025