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Ultrasound Contrast Agents for Stress Echocardiography

N/A

Recruiting

Led By Thomas R Porter, MD

Research Sponsored by University of Nebraska

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

19 years of age or older at screening

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up the data will be obtained within 30 minutes of the echocardiogram or stress echocardiogram. any potential side effects will have occurred within this time frame as well.

Awards & highlights

Study Summary

This trial is testing whether condensedDEFINITY or LUMASON contrast agent can be reactivated by ultrasound so that it can be used during a stress echocardiogram.

Who is the study for?

This trial is for adults 19 or older who need a stress echocardiography test at the UNMC lab. It's not for those who've had allergic reactions to DEFINITY® or LUMASON, or for pregnant women.Check my eligibility

What is being tested?

The study tests if condensed DEFINITY® or LUMASON, used in heart ultrasound tests, can be 'reactivated' with ultrasound after it turns liquid during use. This could make it better suited for current imaging techniques.See study design

What are the potential side effects?

Since this trial uses standard contrast agents (DEFINITY® or LUMASON), side effects may include allergic reactions, but these are rare. Participants will be monitored closely after the test.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Select...

I am 19 years old or older.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ the data will be obtained within 30 minutes of the echocardiogram or stress echocardiogram. any potential side effects will have occurred within this time frame as well.

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~the data will be obtained within 30 minutes of the echocardiogram or stress echocardiogram. any potential side effects will have occurred within this time frame as well.

This trial's timeline: 3 weeks for screening, Varies for treatment, and the data will be obtained within 30 minutes of the echocardiogram or stress echocardiogram. any potential side effects will have occurred within this time frame as well. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Acoustic index

Secondary outcome measures

Clinical Adverse Events regarding reading of echocardiography

Trial Design

1Treatment groups

Experimental Treatment

Group I: Single group, one arm study groupExperimental Treatment1 Intervention

Compare echocardiograph imaging efficacy of active Definity or Lumason (perflutren lipid microsphere) with compressed Definity or Lumason.

0 / 1Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of NebraskaLead Sponsor

539 Previous Clinical Trials

1,144,684 Total Patients Enrolled

Thomas R Porter, MDPrincipal InvestigatorUniversity of Nebraska

10 Previous Clinical Trials

989 Total Patients Enrolled

Thomas Porter, MDPrincipal InvestigatorUniversity of Nebraska

1 Previous Clinical Trials

124 Total Patients Enrolled

Media Library

Single group, one arm study group Clinical Trial Eligibility Overview. Trial Name: NCT02950493 — N/A

Stress Echocardiography Research Study Groups: Single group, one arm study group

Stress Echocardiography Clinical Trial 2023: Single group, one arm study group Highlights & Side Effects. Trial Name: NCT02950493 — N/A

Single group, one arm study group 2023 Treatment Timeline for Medical Study. Trial Name: NCT02950493 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How much of a sample size is the research team aiming to include in this experiment?

"Indeed, the information hosted on clinicaltrials.gov demonstrates that this clinical trial is presently enrolling individuals for participation. This particular study was initially published on December 1st 2016 and has undergone recent amendments made as of March 5th 2022 - with a total of 50 participants expected to be recruited from one medical centre."

Answered by AI

Has this therapy been approved by the relevant governing body?

"The safety of this treatment has been evaluated as a 2 on our internal scale, due to the fact that there is some evidence suggesting its safety but no proof regarding efficacy."

Answered by AI

Is there still capacity for participants in this clinical experiment?

"Affirmative. As evidenced by the clinicaltrials.gov's records, this research is currently open for recruitment with an initial post date of December 1st 2016 and a last update on March 5th 2022. This trial calls for 50 test subjects to be recruited from one location."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Use of Reactivated DEFINITY or LUMASON in Patients Undergoing Rest or Stress Echocardiography

Thomas R. Porter, MD 2016. "Use of Reactivated DEFINITY or LUMASON in Patients Undergoing Rest or Stress Echocardiography". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT02950493.