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Local Anesthetic

Laparoscopic assisted TAP block for Laparoscopic Transversus Abdominis Plane Block Analgesia Efficacy (TAP Trial)

Phase 2

Waitlist Available

Led By Farinaz Seifi, MD, FACOG

Research Sponsored by Yale University

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 48 -72 hours post operative

Awards & highlights

TAP Trial Summary

This trial will help researchers understand if LA-TAP blocks can help manage postoperative pain and if it can help reduce postoperative opioid consumption.

TAP Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 48 -72 hour post operative

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~48 -72 hour post operative

This trial's timeline: 3 weeks for screening, Varies for treatment, and 48 -72 hour post operative for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Amount and type of opioid consumption , based on Questionnaire's information . between LA-TAP , UG-TAP and No TAP groups at 24 hours post operatively

pain scores at 24 hours in LA-TAP and NO TAP block groups

Secondary outcome measures

Nausea and vomiting post operatively , based on questionnaire's information at first 72 h post op

Numeric pain score (NPS) based on questionnaire's information at 48 hours & 72 hours post operatively , in LA-TAP , UG-TAp and no TAP groups

amount of narcotic , per milligram and type of opiod consumption at 48 & 72 hours post operatively ?

TAP Trial Design

2Treatment groups

Active Control

Group I: Laparoscopic assisted TAP blockActive Control1 Intervention

Laparoscopic assisted TAP block will be done by surgeon intra-operatively

Group II: no TAP blockActive Control1 Intervention

no TAP block would be done

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Who is running the clinical trial?

Yale UniversityLead Sponsor

1,851 Previous Clinical Trials

2,738,133 Total Patients Enrolled

Farinaz Seifi, MD, FACOG2.52 ReviewsPrincipal Investigator - Yale University Obstetrics, Gynecology & Reproductive Sciences

Yale University

4Patient Review

She was very patient in answering all my questions and took the time to explain her procedures and reasoning. I appreciate that she was so considerate.

Media Library

TAP block with liposomal bupivacaine and bupivacaine (Local Anesthetic) Clinical Trial Eligibility Overview. Trial Name: NCT04345341 — Phase 2

Laparoscopic Transversus Abdominis Plane Block Analgesia Efficacy Research Study Groups: Laparoscopic assisted TAP block, no TAP block

Laparoscopic Transversus Abdominis Plane Block Analgesia Efficacy Clinical Trial 2023: TAP block with liposomal bupivacaine and bupivacaine Highlights & Side Effects. Trial Name: NCT04345341 — Phase 2

TAP block with liposomal bupivacaine and bupivacaine (Local Anesthetic) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04345341 — Phase 2

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

What conditions can be addressed with Laparoscopic assisted TAP block?

"Utilizing the Laparoscopic assisted TAP block procedure, medical professionals can ameliorate such conditions as pemphigus, acute nonspecific tenosynovitis and general anesthesia."

Answered by AI

Is recruitment still underway for this trial?

"Affirmative. Clinicaltrials.gov displays that this research is actively enrolling participants, with the first postings being made on November 1st 2020 and the most recent update taking place on November 17th 2022. 80 subjects are required from a single clinical site for successful completion of the study."

Answered by AI

Could you elucidate on any prior exploratory experiments involving Laparoscopic assisted TAP block?

"Currently, Laparoscopic assisted TAP block is the subject of 109 ongoing clinical trials including 18 Phase 3 studies. Despite most being located in Pennsylvania's Philadelphia area, 144 distinct medical sites are participating in these trials."

Answered by AI

Has the FDA sanctioned Laparoscopic assisted TAP block for medical use?

"Although there is evidence for Laparoscopic assisted TAP block being safely administered, the lack of supporting efficacy data places its safety score at a 2."

Answered by AI

What is the total population size of this research endeavor?

"Indeed, the data posted to clinicaltrials.gov indicates that this medical trial is actively seeking participants; it was initially listed on November 1st 2020 and most recently updated on November 17th 2022. 80 patients need to be enlisted from a single location."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Efficacy of Laparoscopic-assisted Transversus Abdominus Plane (TAP) Block Compared to Ultrasound-guided TAP Block in Minimally Invasive Gynecologic Surgeries: A Prospective, Randomized Control Trial.

Farinaz Seifi 2020. "Efficacy of Laparoscopic-assisted Transversus Abdominus Plane (TAP) Block Compared to Ultrasound-guided TAP Block in Minimally Invasive Gynecologic Surgeries: A Prospective, Randomized Control Trial.". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04345341.