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Behavioural Intervention

Real-time functional magnetic resonance neurofeedback (rtfMRI-nf) for Post-Traumatic Stress Disorder (SPrC-PTSD Trial)

N/A
Waitlist Available
Led By Robin L Aupperle, Ph.D.
Research Sponsored by Laureate Institute for Brain Research, Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up approximately 2 hours after baseline assessment
Awards & highlights

SPrC-PTSD Trial Summary

This study is evaluating whether a brain stimulation technique can improve emotional cognitive control in people with PTSD.

Eligible Conditions
  • Post-Traumatic Stress Disorder
  • Cognitive Functioning

SPrC-PTSD Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~approximately 2 hours after baseline assessment
This trial's timeline: 3 weeks for screening, Varies for treatment, and approximately 2 hours after baseline assessment for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Left dorsolateral prefrontal cortex activity during emotional cognitive control (pre- to post-neurofeedback)
Secondary outcome measures
Left dorsolateral prefrontal cortex functional connectivity with other brain regions during rest (pre- to post-neurofeedback)
Other outcome measures
Color Word Stroop Average Reaction Time
Color Word Stroop Reaction Time Difference
Emotional Stroop Average Reaction Time
+3 more

SPrC-PTSD Trial Design

1Treatment groups
Experimental Treatment
Group I: Active Left Dorsolateral Prefrontal Cortex rtfMRI-nfExperimental Treatment1 Intervention
Real-time functional magnetic resonance imaging neurofeedback (rtfMRI-nf) will target left dorsolateral prefrontal cortex. Participants in this arm will receive active feedback while attempting to modulate their neural activity during an emotional cognitive control task.

Find a Location

Who is running the clinical trial?

Laureate Institute for Brain Research, Inc.Lead Sponsor
50 Previous Clinical Trials
5,345 Total Patients Enrolled
Robin L Aupperle, Ph.D.Principal InvestigatorLaureate Institute for Brain Research
3 Previous Clinical Trials
248 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Who else is applying?

What state do they live in?
Texas
Oklahoma
How old are they?
18 - 65
What site did they apply to?
Laureate Institute for Brain Research
What portion of applicants met pre-screening criteria?
Met criteria

How responsive is this trial?

Average response time
  • < 2 Days
Most responsive sites:
  1. Laureate Institute for Brain Research: < 48 hours
Typically responds via
Email
Recent research and studies
clinicaltrials.govStudy
Self-regulation of Prefrontal Cortex During Emotional Cognitive Control in PTSD
Robin Aupperle 2023. "Self-regulation of Prefrontal Cortex During Emotional Cognitive Control in PTSD". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04543513.
~0 spots leftby Apr 2025
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