Targeted memory reactivation (sounds) for Sleep

Phase-Based Progress Estimates
1
Effectiveness
1
Safety
Sleep+1 More
Targeted memory reactivation (sounds) - Behavioral
Eligibility
18 - 65
All Sexes
What conditions do you have?
Select

Study Summary

This trial is testing whether sleep can be used to weaken non-adaptive memories, which may be helpful for people with memory-related symptoms of disorders like PTSD.

Eligible Conditions
  • Sleep
  • Consolidation

Treatment Effectiveness

Effectiveness Progress

1 of 3

Study Objectives

2 Primary · 0 Secondary · Reporting Duration: Approximately 15 minutes before sleep onset and approximately 15 minutes after sleep offset within the same experimental session

Approximately 15 minutes before sleep onset and approximately 15 minutes after sleep offset within the same experimental session
Change in error rates between pre- and post-sleep for the different conditions
Hour 5
Modulation of EEG spectral power following sound/odor presentation

Trial Safety

Safety Progress

1 of 3

Trial Design

1 Treatment Group

Experimental group
1 of 1
Experimental Treatment

38 Total Participants · 1 Treatment Group

Primary Treatment: Targeted memory reactivation (sounds) · No Placebo Group · N/A

Experimental groupExperimental Group · 2 Interventions: Targeted memory reactivation (sounds), Targeted memory reactivation (odors) · Intervention Types: Behavioral, Behavioral
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Targeted memory reactivation (sounds)
2021
N/A
~70

Trial Logistics

Trial Timeline

Approximate Timeline
Screening: ~3 weeks
Treatment: Varies
Reporting: approximately 15 minutes before sleep onset and approximately 15 minutes after sleep offset within the same experimental session

Who is running the clinical trial?

Northwestern UniversityLead Sponsor
1,432 Previous Clinical Trials
769,499 Total Patients Enrolled
6 Trials studying Sleep
583 Patients Enrolled for Sleep

Eligibility Criteria

Age 18 - 65 · All Participants · 1 Total Inclusion Criteria

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About The Reviewer

Michael Gill preview

Michael Gill - B. Sc.

First Published: October 6th, 2021

Last Reviewed: October 19th, 2022

Michael Gill holds a Bachelors of Science in Integrated Science and Mathematics from McMaster University. During his degree he devoted considerable time modeling the pharmacodynamics of promising drug candidates. Since then, he has leveraged this knowledge of the investigational new drug ecosystem to help his father navigate clinical trials for multiple myeloma, an experience which prompted him to co-found Power Life Sciences: a company that helps patients access randomized controlled trials.