ESP Block for Pain Management
What You Need to Know Before You Apply
What is the purpose of this trial?
This trial aims to evaluate the effectiveness of a specific type of pain relief, called an ESP block (Erector Spinae Plane Block), after surgery. Researchers seek to determine the duration of pain relief and the optimal dosage of the medication. Healthy individuals who are generally free from medical problems and do not use recreational drugs may qualify for this trial. Volunteers will receive two different doses of a numbing medication and will be monitored for pain relief effects on the chest or abdominal area. As an unphased study, this trial allows participants to contribute to innovative pain management research.
Do I need to stop my current medications for the trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
What prior data suggests that the ESP block is safe for pain management?
Research has shown that the erector spinae plane (ESP) block, when used with 1.5% lidocaine, is generally well-tolerated. This method has been tested in various situations and has produced good results in managing both short-term and long-term pain. A review of several studies found that ESP blocks effectively reduce pain after surgeries, leading to less need for pain medication during recovery.
Some studies report that patients are more satisfied with the pain relief from the ESP block compared to other methods. While side effects like numbness or temporary weakness can occur, they are usually mild and resolve on their own. The lidocaine used in this treatment is a common local anesthetic that has been safely used for many years in various medical procedures.
In summary, the ESP block with 1.5% lidocaine appears to be a safe option for managing pain, with most side effects being mild and temporary.12345Why are researchers excited about this trial?
Researchers are excited about the ESP Block with lidocaine for pain management because it offers a targeted approach to pain relief, potentially reducing the need for systemic painkillers like opioids. Unlike traditional pain treatments that often rely on oral medications affecting the whole body, the ESP Block involves delivering the anesthetic directly to the erector spinae plane near the spine, which can provide localized pain relief with fewer side effects. This method could lead to personalized pain management strategies, as the study explores the effects of different volumes of lidocaine to optimize patient outcomes. By focusing on a specific area, this technique aims to offer quicker and more effective pain relief, which could be a game-changer for patients seeking alternatives to standard treatments.
What evidence suggests that the ESP block is effective for pain management?
Research has shown that the erector spinae plane (ESP) block is a promising method for pain relief, particularly after surgeries. Studies have found that this block can reduce the need for opioids during and after surgery, offering a significant advantage in pain management. For instance, patients who received an ESP block reported feeling better 24 hours post-surgery. The ESP block numbs nerves in a specific part of the back, helping control pain in nearby areas. Although still relatively new, early results are encouraging regarding its effectiveness in managing pain. In this trial, participants will receive different volumes of 1.5% lidocaine with the ESP block to assess its effectiveness in pain management.678910
Who Is on the Research Team?
Ki Jinn Chin, MBBS, MMed,FRCPC
Principal Investigator
UHN
Are You a Good Fit for This Trial?
Healthy volunteers aged 18-50, weighing between 65-100 kg, and fluent in English can participate. Women able to have children must test negative for pregnancy and agree to use birth control during the study.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Treatment
Participants receive unilateral ESP block with different local anesthetic volumes across two visits
Follow-up
Participants are monitored for the duration and regression of sensory blockade post-ESP block
What Are the Treatments Tested in This Trial?
Interventions
- 1.5% Lidocaine
- Erector Spinae Plane Block
Trial Overview
The trial is testing how well an ESP block with lidocaine manages pain after surgery. Volunteers will receive two different doses of the anesthetic at separate visits to see which works better for chest or abdominal wall pain relief.
How Is the Trial Designed?
2
Treatment groups
Experimental Treatment
(2) Group 30/20: a unilateral ESP block with 30 mL of 1.5% lidocaine with 1/200,000 epinephrine at the first visit, and 20 mL of the same local anesthetic solution at the second visit. This crossover design allows subjects to serve as their own control.
Two different local anesthetic volumes will be investigated: 20 mL of 1.5% lidocaine (300 mg lidocaine) at one study visit and 30 mL of 1.5% lidocaine (450 mg lidocaine) at the other study visit. Volunteers will be randomized to one of two intervention groups: (1) Group 20/30: A unilateral ESP block with 20 mL of local anesthetic at the first visit, and 30 mL of local anesthetic at the second visit
Find a Clinic Near You
Who Is Running the Clinical Trial?
University Health Network, Toronto
Lead Sponsor
Citations
Erector Spinae Plane Block - StatPearls - NCBI Bookshelf
The erector spinae plane block is a newer regional anesthesia technique that can be used to provide analgesia for various surgical procedures or to manage ...
The efficacy of lumbar erector spinae plane block for ...
US-guided L-ESPB reduces intraoperative and 24 h postoperative opioid consumption and improves patients' QoR-15 scores at 24 h postoperatively.
Ultrasound Guided Erector Spinae Plane Block for Pain ...
Clinical Reviews. Ultrasound Guided Erector Spinae Plane Block for Pain Management in the Emergency Department: A Scoping Review.
A randomized clinical trial of erector spinae plane block ...
The primary hypothesis of this study was that ESPB reduces the incidence of chronic pain for 3 months after posterior lumbar surgery.
5.
janesthanalgcritcare.biomedcentral.com
janesthanalgcritcare.biomedcentral.com/articles/10.1186/s44158-024-00205-yUltrasound-guided fascial plane blocks in chronic pain
We conducted a systematic literature search (updated on February 2024) to evaluate the role of fascial plane blocks in chronic pain treatment.
Efficacy and Safety of Erector Spinae Plane Block ...
This meta-analysis demonstrated that ESPB used in lumbar spinal surgery was effective in relieving postoperative pain, decreasing the perioperative consumption ...
Erector Spinae Plane (ESP) Block Volunteer Study
The goal of this study is to determine the extent and duration of clinical neural blockade following an ESP injection with different local anesthetic doses.
The erector spinae plane block: a narrative review - PMC
Many cases of its use have been described with satisfactory results in the treatment of both acute pain and chronic pain. The applicability of the technique ...
Comparison of the Analgesic Efficacy of Erector
Objective: This study compared the analgesic efficacy of the erector spinae plane block (ESPB), thoracic paravertebral block (TPVB), and quadratus lumborum ...
10.
bmcanesthesiol.biomedcentral.com
bmcanesthesiol.biomedcentral.com/articles/10.1186/s12871-022-01860-wAnalgesia and spread of erector spinae plane block in ...
The current study demonstrated that ESPB results in a higher level of satisfaction among patients compared to GA alone, yet the difference in ...
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