210 Participants NeededMy employer runs this trial

GIA632 for Vitiligo

(VITESS Trial)

Recruiting at 17 trial locations
Age: 18+
Sex: Any
Trial Phase: Phase 2
Sponsor: Novartis Pharmaceuticals
Prior Safety DataThis treatment has passed at least one previous human trial

What You Need to Know Before You Apply

What is the purpose of this trial?

The main purpose of this multicenter, randomized, double-blind, placebo-controlled Phase 2b study is to investigate the safety and efficacy of GIA632 in participants with NSV and to identify the optimal dose to be promoted into the confirmatory Phase 3 program.

Are You a Good Fit for This Trial?

Inclusion Criteria

* Signed informed consent must be obtained prior to participation in the study
I am 18 years old or older.
I have non-segmental vitiligo confirmed by a doctor and visible spots on my face.
See 1 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive GIA632 or placebo during the 48-week core period to assess dose-response relationship and treatment effect

48 weeks

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

Extension

Assessment of longer-term safety and efficacy in an extension period

What Are the Treatments Tested in This Trial?

Interventions

  • GIA632

How Is the Trial Designed?

5

Treatment groups

Experimental Treatment

Placebo Group

Group I: GIA632 Arm 4Experimental Treatment1 Intervention
Group II: GIA632 Arm 3Experimental Treatment1 Intervention
Group III: GIA632 Arm 2Experimental Treatment1 Intervention
Group IV: GIA632 Arm 1Experimental Treatment1 Intervention
Group V: PlaceboPlacebo Group1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Novartis Pharmaceuticals

Lead Sponsor

Trials
2,963
Recruited
4,275,000+
Founded
1996
Headquarters
Basel, Switzerland
Known For
Precision medicine
Top Products
Gleevec, Cosentyx, Entresto, Kisqali
Dr. Vas Narasimhan profile image

Dr. Vas Narasimhan

Novartis Pharmaceuticals

Chief Executive Officer since 2018

MD from Harvard Medical School

Dr. Shreeram Aradhye profile image

Dr. Shreeram Aradhye

Novartis Pharmaceuticals

Chief Medical Officer since 2021

MD