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Conjugate Vaccine

24 valent pneumococcal conjugate vaccine for Pneumococcal Vaccines

Phase 1 & 2
Waitlist Available
Research Sponsored by Vaxcyte, Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 7 days after vaccination
Awards & highlights

Study Summary

This trial is testing a new vaccine for adults, to see if it is safe and effective. The new vaccine will be compared to an existing one to see if it works better.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~7 days after vaccination
This trial's timeline: 3 weeks for screening, Varies for treatment, and 7 days after vaccination for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Mental disorders
Percentage of participants reporting solicited local reactions within 7 days after vaccination in each age group
Vaccination
+1 more
Secondary outcome measures
24 VAX-24 Pneumococcal serotype-specific IgG geometric mean concentration (GMCs)
24 VAX-24 Pneumococcal serotype-specific opsonophagocytic assay (OPA) geometric mean titer (GMTs)
Percentage of participants with laboratory value abnormalities and/or potentially clinically significant laboratory values

Trial Design

4Treatment groups
Experimental Treatment
Active Control
Group I: Group 3Experimental Treatment1 Intervention
Participants will receive a single dose of VAX-24 administered as an intramuscular injection on Day 1 at one of three dose levels.
Group II: Group 2Experimental Treatment1 Intervention
Participants will receive a single dose of VAX-24 administered as an intramuscular injection on Day 1 at one of three dose levels.
Group III: Group 1Experimental Treatment1 Intervention
Participants will receive a single dose of VAX-24 administered as an intramuscular injection on Day 1 at one of three dose levels.
Group IV: Group 4Active Control1 Intervention
Participants will receive a single intramuscular injection of the standard dose of PCV20 on Day 1.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
24 valent pneumococcal conjugate vaccine
2022
Completed Phase 2
~780

Find a Location

Logistics

Participation is compensated

You will be compensated for participating in this trial.

Who is running the clinical trial?

Vaxcyte, Inc.Lead Sponsor
3 Previous Clinical Trials
2,022 Total Patients Enrolled
Clinical DevelopmentStudy DirectorVaxcyte, Inc.
34 Previous Clinical Trials
87,873 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any available slots left for participants in this research project?

"This study is not recruiting patients at the moment, however this could change in the future. According to clinicaltrials.gov, this trial was first posted on February 22nd, 2022 and was last edited on July 25th, 2022. There are 5 other similar trials that are currently looking for participants."

Answered by AI

Might I be able to join this clinical research project?

"This study is looking for 864 people, between the ages of 18 and 64 who have vaccines, pneumococcal. It is important that patients also meet the following criteria: Able and willing to complete the informed consent process., Available for clinical follow-up through the last study visit at 6 months after the study vaccination., Screening laboratory values must be within the central laboratory normal limits prior to study enrollment. Minor abnormalities are considered acceptable if not clinically significant., Able to provide proof of identity to the satisfaction of the study staff completing the enrollment process., Negative pregnancy test (urine and serum) for women of childbearing potential., Male"

Answered by AI

Does this research require participants to be a certain age?

"The ideal candidate for this clinical trial is someone who is under 64 years old and has already celebrated their 18th birthday."

Answered by AI

Is this clinical study taking place primarily in the United States?

"In addition to Precision Clinical Research in Sunrise, Florida, Acellacare of Wilmington in Wilmington, North carolina, and Benchmark Research in San Angelo, Texas; this study is also enrolling patients at 13 other sites."

Answered by AI
~250 spots leftby Apr 2025