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Unknown

RTX-224 for Skin Cancer

Phase 1 & 2

Waitlist Available

Research Sponsored by Rubius Therapeutics

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 30 months

Awards & highlights

Study Summary

This trial is testing a new drug, RTX-224, to see if it can help people with solid tumors that have come back or are not responding to other treatments.

Eligible Conditions

Skin Cancer
Head and Neck Squamous Cell Carcinoma
Breast Cancer
Bladder Cancer
Non-Small Cell Lung Cancer

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 30 months

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 30 months

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 30 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Dose limiting toxicities (DLTs) of RTX-224

Safety Assessment by rate of Adverse Events (AEs)

Secondary outcome measures

Anti-tumor activity of RTX-224

Pharmacodynamics (PD) of RTX-224

Pharmacokinetics (PK) of RTX-224

Trial Design

2Treatment groups

Experimental Treatment

Group I: RTX-224 Dose ExpansionExperimental Treatment1 Intervention

Phase 2: RTX-224 monotherapy dose expansion in Solid Tumors, administered intravenously on Day 1 of each cycle.

Group II: RTX-224 Dose EscalationExperimental Treatment1 Intervention

Phase 1: RTX-224 monotherapy dose escalation in Solid Tumors, administered intravenously on Day 1 of each cycle.

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Rubius TherapeuticsLead Sponsor

3 Previous Clinical Trials

79 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is this research project limited to a few hospitals in the United States?

"To make things more convenient for patients, the 5 sites conducting this trial are situated in or near Los Angeles, San Francisco and Nashville. There are also other participating clinics located in 5 additional cities."

Answered by AI

Are there any current vacancies for volunteers in this experiment?

"Unfortunately, this study is not recruiting patients at the moment. However, there have been 3599 other clinical trials posted in the past that may be of interest."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

RTX-224 Monotherapy in Patients With Solid Tumors

2022. "RTX-224 Monotherapy in Patients With Solid Tumors". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05219578.