243 Participants Needed

INV-202 for Obesity and Metabolic Syndrome

Recruiting at 23 trial locations
GC
KL
Overseen ByKarine Lalonde
Prior Safety DataThis treatment has passed at least one previous human trial

What You Need to Know Before You Apply

What is the purpose of this trial?

The study is designed to assess the efficacy, safety, tolerability, and transformation within the human body of INV-202 investigational drug in the treatment of adult participants with obesity and metabolic syndrome.

Who Is on the Research Team?

CT

Clinical Transparency (dept. 2834)

Principal Investigator

Novo Nordisk A/S

Are You a Good Fit for This Trial?

Adults aged 18-75 with obesity (BMI ≥ 30) and metabolic syndrome, having at least three of these: large waist size, high fasting glucose or HgbA1C, abnormal triglycerides or HDL levels, hypertension. Must not have had significant weight changes recently, be on certain medications including weight-loss drugs or have serious health issues like liver disease, epilepsy, active substance abuse, severe psychiatric disorders.

Inclusion Criteria

You have a body mass index (BMI) of 30 or higher.
Able and willing to provide informed consent and to comply with scheduled visits and study procedures
I meet at least 3 of the criteria for metabolic syndrome.

Exclusion Criteria

You have a current or past serious mental health condition.
My medications for blood pressure, cholesterol, or blood sugar have been stable for the last 3 months.
I am not taking medication that strongly affects certain liver enzymes.
See 16 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks
1 visit (in-person), with possible retest

Treatment

Participants receive INV-202 or placebo with assessments at Weeks 4, 8, 12, and 16

16 weeks
4 visits (in-person)

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

Open-label extension

Participants may continue receiving INV-202 for further evaluation of efficacy and safety

36 weeks
Regular visits (in-person)

What Are the Treatments Tested in This Trial?

Interventions

  • INV-202
Trial Overview The trial is testing INV-202 against a placebo to see if it's effective and safe for treating obesity and metabolic syndrome. Participants will either receive the investigational drug INV-202 or a placebo without knowing which one they are getting.
How Is the Trial Designed?
4Treatment groups
Experimental Treatment
Placebo Group
Group I: Middle DoseExperimental Treatment1 Intervention
Group II: Low doseExperimental Treatment1 Intervention
Group III: High doseExperimental Treatment1 Intervention
Group IV: PlaceboPlacebo Group2 Interventions

Find a Clinic Near You

Who Is Running the Clinical Trial?

Inversago Pharma Inc.

Lead Sponsor

Trials
4
Recruited
590+
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top
Terms of Service·Privacy Policy·Cookies·Security