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Radiation Therapy + Hyperbaric Oxygen for Glioblastoma

Phase 1 & 2
Waitlist Available
Research Sponsored by Barrett Cancer Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Histologically proven newly diagnosed glioblastoma multiforme
Age over 18
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights

Study Summary

This trial is studying how well combining radiation therapy with hyperbaric oxygen works in treating patients with newly diagnosed glioblastoma multiforme.

Who is the study for?
This trial is for adults over 18 with a new diagnosis of glioblastoma multiforme, confirmed by tissue analysis. Participants should have some remaining tumor visible on MRI after initial surgery, be in good physical condition (Karnofsky score 70-100%), and expected to live more than 8 weeks. It's not for those with severe lung disease, untreated collapsed lung, pregnant or nursing women, recent other cancers except skin cancer, uncontrolled seizures, or prior treatments for their brain tumor.Check my eligibility
What is being tested?
The study is testing the combination of radiation therapy with hyperbaric oxygen treatment in patients with newly diagnosed glioblastoma multiforme. The goal is to see if breathing pure oxygen under high pressure can boost the effectiveness of radiation in targeting brain tumor cells.See study design
What are the potential side effects?
Potential side effects may include fatigue from radiation therapy and ear pain or sinus discomfort due to increased pressure during hyperbaric oxygen treatment. There might also be a risk of oxygen toxicity which can affect the lungs and central nervous system.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I have been newly diagnosed with glioblastoma.
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I am over 18 years old.
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I am mostly able to care for myself and carry out daily activities.
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I have a tumor that can still be seen on an MRI after surgery or biopsy.
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I haven't had any cancer except skin cancer in the last 5 years.
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I do not have uncontrollable seizures.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Find a Location

Who is running the clinical trial?

Barrett Cancer CenterLead Sponsor
3 Previous Clinical Trials
60 Total Patients Enrolled
Ronald E. Warnick, MDStudy ChairBarrett Cancer Center
1 Previous Clinical Trials
30 Total Patients Enrolled

Media Library

Radiation Therapy Clinical Trial Eligibility Overview. Trial Name: NCT00006460 — Phase 1 & 2
Brain Tumor Research Study Groups:
Brain Tumor Clinical Trial 2023: Radiation Therapy Highlights & Side Effects. Trial Name: NCT00006460 — Phase 1 & 2
Radiation Therapy 2023 Treatment Timeline for Medical Study. Trial Name: NCT00006460 — Phase 1 & 2

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there still spaces available for participants in this trial?

"According to clinicaltrials.gov, this medical trial is not accepting new patients at the present moment. This research was initially posted on August 1st 2000 and last edited December 3rd 2013. Nevertheless, there are 543 other studies actively recruiting candidates right now."

Answered by AI
Recent research and studies
clinicaltrials.govStudy
Radiation Therapy Plus Hyperbaric Oxygen in Treating Patients With Newly Diagnosed Glioblastoma Multiforme
2000. "Radiation Therapy Plus Hyperbaric Oxygen in Treating Patients With Newly Diagnosed Glioblastoma Multiforme". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT00006460.
All > Ic
~14 spots leftby Apr 2025
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