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AZD7648 for Cancer
Study Summary
This trial is testing a new drug, AZD7648, to see if it can treat cancer either by itself or in combination with other drugs.
- Cancer
Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2022 Phase 1 & 2 trial • 30 Patients • NCT03907969Trial Design
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Who is running the clinical trial?
Frequently Asked Questions
Does your research project have an upper age limit for participants?
"This trial is recruiting individuals aged 18-130."
What other researches have been conducted regarding the effects of AZD7648?
"AZD7648 was first studied in 1997 at the Spectrum Health Butterworth Campus, and since then 678 clinical trials have been completed. At present there are 360 active studies worldwide, with a concentration of research occurring in New Haven, Connecticut."
What is the utmost capacity of participants in this trial?
"At this time, enrollment for the referenced study is closed. Originally posted on October 9th 2019 and last edited November 9th 2022, other options exist with 2376 trials recruiting patients suffering from advanced forms of cancer and 360 studies enrolling participants taking AZD7648 as a treatment option."
What goals are being pursued through this clinical investigation?
"This clinical trial has two primary objectives. The first is to measure the number of participants with adverse events/serious adverse events over each 28-day cycle, and the second is to characterise AZD7648's pharmacokinetics when given monotherapy or alongside anti-cancer agents by measuring AUC from zero to last measurable concentration (AUCtau), time to reach maximum plasma concentration (Tmax) and progression-free survival (PFS)."
Are there any opportunities to join this trial currently available?
"Data published on clinicaltrials.gov reveals that this particular medical trial, which began recruitment in October 2019 and ended in November 2022 is no longer accepting applicants. However, a plethora of other trials (2736 to be exact) are still recruiting patients at present."
Who qualifies for enrollment in this trial?
"To qualify for this medical experiment, participants should possess an advanced form of cancer and be between 18 to 130 years old. A maximum of 30 volunteers will be accepted."
Has there been precedent for this sort of research before?
"Alfacell first initiated the clinical trials for AZD7648 in 1997, which included 300 participants. Consequently, after successful Phase 3 approval was granted to AZD7648 and as of today, 66 countries across 1941 cities are running 360 active studies related to this medication."
What therapeutic applications does AZD7648 typically address?
"AZD7648 has been successfully employed to treat various forms of cancer, including lymphoma, Hodgkin's disease, bronchogenic carcinoma and neuroblastoma."
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