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Treatment for Prostate Cancer

Phase 1 & 2
Waitlist Available
Led By Michael Milosevic, MD
Research Sponsored by University Health Network, Toronto
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up once at time of imaging
Awards & highlights

Study Summary

This trial is testing whether a new contrast agent can help improve MRI imaging of lymph nodes in the pelvis, as well as help doctors determine if cancer has spread to these lymph nodes. If successful, this could lead to more accurate delivery of radiotherapy.

Eligible Conditions
  • Prostate Cancer
  • Uterine Cancer
  • Cervical Cancer
  • Bladder Cancer

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~once at time of imaging
This trial's timeline: 3 weeks for screening, Varies for treatment, and once at time of imaging for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Improved clinical target volume (CTV) definition for the purpose of adjuvant irradiation of pelvic lymph nodes using intensity modulated radiotherapy (IMRT).
Improved delineation of normal pelvic lymph nodes in patients with uterine, cervical, bladder and prostate cancers.
Secondary outcome measures
Comparison of target lymph node delineation between nodal imaging with USPIO and volume expansion of vascular anatomy.
Demonstration of the pattern and distribution of pelvic nodal metastases in patients with uterine, cervical, bladder and prostate cancers.

Find a Location

Who is running the clinical trial?

University Health Network, TorontoLead Sponsor
1,476 Previous Clinical Trials
485,119 Total Patients Enrolled
64 Trials studying Prostate Cancer
15,400 Patients Enrolled for Prostate Cancer
Princess Margaret Hospital, CanadaOTHER
119 Previous Clinical Trials
38,998 Total Patients Enrolled
10 Trials studying Prostate Cancer
9,916 Patients Enrolled for Prostate Cancer
Michael Milosevic, MDPrincipal InvestigatorPrincess Margaret Hospital, Canada
10 Previous Clinical Trials
1,087 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Combidex USPIO - Ultra-small Superparamagnetic Iron Oxide
2004. "Combidex USPIO - Ultra-small Superparamagnetic Iron Oxide". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT00188695.
~3 spots leftby Apr 2025
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