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NUV-422 for Brain Tumor

Phase 1
Waitlist Available
Research Sponsored by Nuvation Bio Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up during the dlt period (28 days)
Awards & highlights

Study Summary

This trial is testing a new drug, NUV-422, to see if it is safe and effective in treating adults with various types of cancer. Patients will take the drug orally every 28 days until the trial ends.

Eligible Conditions
  • Brain Tumor
  • Gliomas
  • Breast Cancer
  • Prostate Cancer
  • Glioblastoma
  • Malignant Glioma

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~during the dlt period (28 days)
This trial's timeline: 3 weeks for screening, Varies for treatment, and during the dlt period (28 days) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Phase 1 Dose Escalation: Safety and tolerability of NUV-422 to determine the recommended Phase 2 dose (RP2D)

Trial Design

1Treatment groups
Experimental Treatment
Group I: Phase 1 Dose EscalationExperimental Treatment1 Intervention
NUV-422 will be administered at escalating dose levels until the maximum tolerated dose (MTD) is reached.

Find a Location

Who is running the clinical trial?

Nuvation Bio Inc.Lead Sponsor
4 Previous Clinical Trials
1,123 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Study of NUV-422 in Adults With Recurrent or Refractory High-grade Gliomas and Solid Tumors
2020. "Study of NUV-422 in Adults With Recurrent or Refractory High-grade Gliomas and Solid Tumors". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04541225.
~17 spots leftby Apr 2025
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