Surgical resection for Sinonasal Melanoma

Phase-Based Progress Estimates
1
Effectiveness
2
Safety
Sinonasal MelanomaSurgical resection - Procedure
Eligibility
18+
All Sexes
What conditions do you have?
Select

Study Summary

This trial is testing if radiation therapy before surgery can improve outcomes for people with sinonasal melanoma.

Eligible Conditions
  • Sinonasal Melanoma

Treatment Effectiveness

Study Objectives

1 Primary · 0 Secondary · Reporting Duration: through study completion an average of 1 year

Year 1
Rate of Pathologic Response

Trial Safety

Safety Progress

2 of 3
This is further along than 68% of similar trials

Trial Design

1 Treatment Group

Surgical resection
1 of 1

Experimental Treatment

40 Total Participants · 1 Treatment Group

Primary Treatment: Surgical resection · No Placebo Group · Phase 2

Surgical resection
Procedure
Experimental Group · 1 Intervention: Surgical resection · Intervention Types: Procedure
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Surgical resection
2021
Completed Phase 2
~920

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: through study completion an average of 1 year

Who is running the clinical trial?

M.D. Anderson Cancer CenterLead Sponsor
2,802 Previous Clinical Trials
1,788,859 Total Patients Enrolled
Devarati Mitra, MDStudy ChairM.D. Anderson Cancer Center

Eligibility Criteria

Age 18+ · All Participants · 10 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
You have histologically or cytologically confirmed melanoma involving the nasal cavity and/or paranasal sinuses.
Patients must have a baseline skull base MRI unless contraindicated by medical or financial toxicity.
Men who are treated on this protocol must also agree to use adequate contraception prior to the study, for the duration of study participation, and 6 months after completion of RT.