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Gene Therapy

FLT190 for Fabry Disease (MARVEL1 Trial)

Phase 1 & 2

Waitlist Available

Research Sponsored by Freeline Therapeutics

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up from screening to 12 weeks post infusion

Awards & highlights

MARVEL1 Trial Summary

This trial looks at a drug for treating a rare disorder in men. It evaluates safety & effectiveness.

Eligible Conditions

Fabry Disease
Lysosomal Storage Diseases

MARVEL1 Trial Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ from screening to 12 weeks post infusion

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~from screening to 12 weeks post infusion

This trial's timeline: 3 weeks for screening, Varies for treatment, and from screening to 12 weeks post infusion for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Frequency of treatment-emergent adverse events (AEs)

MARVEL1 Trial Design

1Treatment groups

Experimental Treatment

Group I: FLT190Experimental Treatment1 Intervention

FLT190 is a recombinant adeno- associated viral (AAV) vector. Administered by a single intravenous infusion.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

FLT190

2020

Completed Phase 2

~10

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Freeline TherapeuticsLead Sponsor

5 Previous Clinical Trials

74 Total Patients Enrolled

1 Trials studying Fabry Disease

3 Patients Enrolled for Fabry Disease

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any open spots remaining for the clinical trial?

"Clinicaltrials.gov confirms that, as of February 14th 2023, this medical trial is recruiting candidates with its inception having occurred on July 8th 2019."

Answered by AI

How many research centers are administering the experiment?

"The research for this trial is being conducted at Columbia University in New york, UPMC Children's Hospital of Pittsburgh in Pennsylvania, and the Lysosomal and Rare Disorders Research and Treatment Center in Virginia. Additionally, there are another 5 sites involved with the study."

Answered by AI

How many participants have been recruited for this research project?

"Affirmative. Clinicaltrials.gov records verify that this clinical trial is actively seeking candidates as of February 14th 2023, shortly after it was initially published on July 8 2019. This research needs to enrol 15 individuals across 5 various sites."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

A Fabry Disease Gene Therapy Study

2019. "A Fabry Disease Gene Therapy Study". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04040049.