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Polyphenol

Resveratrol for High Blood Pressure

Phase 1 & 2

Waitlist Available

Led By Ajoy C Karikkineth, M.D.

Research Sponsored by National Institute on Aging (NIA)

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up week 16, 32, 52

Awards & highlights

Study Summary

This trial is testing the effects of different dose levels of Resveratrol on heart and blood vessel health in healthy overweight people.

Eligible Conditions

High Blood Pressure
Vascular Resistance

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ week 16, 32, 52

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~week 16, 32, 52

This trial's timeline: 3 weeks for screening, Varies for treatment, and week 16, 32, 52 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

To determine if oral resveratrol administered for 12 months will blunt the aging associated increase in vascular stiffness as measured by Pulse Wave Velocity (PWV).

Secondary outcome measures

To determine if oral resveratrol administered for 12 months will improve exercise capacity as measured by MVO2-treadmill.

Side effects data

From 2013 Phase 2 trial • 24 Patients • NCT02114892

25%

Headache

Abdominal pain

Sickness

100%

80%

60%

40%

20%

Study treatment Arm

Resveratrol

Placebo

Trial Design

3Treatment groups

Experimental Treatment

Placebo Group

Group I: Resveratrol 2Experimental Treatment1 Intervention

150 mg, 2x/day orally

Group II: Resveratrol 1Experimental Treatment1 Intervention

75 mg, 2x/day orally

Group III: Placebo ComparatorPlacebo Group1 Intervention

2x/day orally

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Resveratrol

2014

Completed Phase 3

~730

Do I qualify?Apply below to find out

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Logistics

Participation is compensated

You will be compensated for participating in this trial.

Who is running the clinical trial?

National Institute on Aging (NIA)Lead Sponsor

1,668 Previous Clinical Trials

28,004,991 Total Patients Enrolled

Ajoy C Karikkineth, M.D.Principal InvestigatorNational Institute on Aging (NIA)

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many participants are currently involved in this clinical experiment?

"Affirmative. According to information available on clinicaltrials.gov, the research is currently welcoming participants, with initial postings dating back to July 14th 2015 and recent updates made on November 19th 2022. 300 individuals are being recruited for participation at a single location."

Answered by AI

Is enrollment still available for this research study?

"As per information displayed on clinicaltrials.gov, enrolment for this medical trial is ongoing. It was first announced in July 2015 and the last update to its entry was posted nearly two years ago in November 2022."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Resveratrol and Cardiovascular Health in the Elderly

2015. "Resveratrol and Cardiovascular Health in the Elderly". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01842399.