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Stem Cell Therapy

CPCB-RPE1 for Macular Degeneration

Phase 1 & 2
Waitlist Available
Research Sponsored by Regenerative Patch Technologies, LLC
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 1 year
Awards & highlights

Study Summary

This trial is designed to assess the feasibility of delivery and safety of Human Embryonic Stem Cell-Derived RPE Cells on a parylene membrane in patients with advanced, dry age-related macular degeneration.

Eligible Conditions
  • Macular Degeneration
  • Age-Related Macular Degeneration

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~1 year
This trial's timeline: 3 weeks for screening, Varies for treatment, and 1 year for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Frequency and Severity of Treatment-Related Adverse Events [Safety and Tolerability]
Secondary outcome measures
Photoreceptor Electrical Responses
Visual Acuity
Visual Field

Trial Design

1Treatment groups
Experimental Treatment
Group I: CPCB-RPE1 treatmentExperimental Treatment1 Intervention
Subretinal implantation of CPCB-RPE1 in dry AMD patients

Find a Location

Who is running the clinical trial?

Regenerative Patch Technologies, LLCLead Sponsor
Jane Lebkowski, Ph.D.Study DirectorRegenerative Patch Technologies

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there any available openings for participants in this clinical trial?

"Unfortunately, the information on clinicaltrials.gov appears to show that this particular trial is not actively seeking participants at this time; it was first posted in February of 2016 and last updated May 27th 2020. Nevertheless, there are currently 319 other studies available for enrollment."

Answered by AI

In what geographic areas is this research endeavor taking place?

"Currently, this research initiative is accepting patients from 6 medical sites. These are located in Santa Barbara, Beverly Hills and Palm Desert among other areas. To minimize travelling demands associated with joining the trial, pick a study location that is closest to you."

Answered by AI

Does this study allow for the enrolment of adults?

"The requirements for this medical trial are that patients must be between 55 and 85 years of age. For those under 18, there are 51 trials available; whereas 266 studies accept participants above the senior citizen threshold."

Answered by AI

Could I meet the criteria for enrollment in this experiment?

"This clinical trial is admitting 16 participants, aged 55 to 85, who have dry macular degeneration. To be eligible for the study, these individuals must also meet many other criteria including: having physical evidence of at least 1.25 square millimeters of geographic atrophy in their eye; not being employees of any related medical sites; possessing enough good health so as to reasonably expect survival over five years post-treatment; having a best-corrected visual acuity (BCVA) score equal or worse than 20/200 and between 20/80 and 20/400 in the second half of patients respectively; medically suitable for surgical implant procedures"

Answered by AI
~2 spots leftby Apr 2025