75 Participants Needed

Tele-exercise for Brain Cancer Survivors

Age: 18 - 65
Sex: Any
Trial Phase: Academic
Sponsor: M.D. Anderson Cancer Center
No Placebo GroupAll trial participants will receive the active study treatment (no placebo)

What You Need to Know Before You Apply

What is the purpose of this trial?

This trial explores how a special exercise program, called RISE-YA, can reduce fatigue in young adults who have survived brain cancer. Researchers aim to determine if regular, supervised exercise sessions conducted remotely can help manage the tiredness often experienced after cancer treatment. The trial includes two groups: one will participate in the exercise program, while the other will receive standard care for comparison. Individuals who have completed treatment for brain cancer, currently feel fatigued, and engage in less than 150 minutes of physical activity per week might be suitable for this study. As a Phase 2 trial, this research focuses on measuring the effectiveness of the exercise program in an initial, smaller group of participants.

Will I have to stop taking my current medications?

The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your healthcare provider.

What prior data suggests that the RISE-YA intervention is safe for brain cancer survivors?

Research shows that exercising during and after cancer treatment is safe and beneficial, especially for young adults. Studies have found that a 10-week supervised exercise program can boost strength and improve quality of life for young cancer patients.

The RISE-YA program, a virtually supervised exercise plan, has not reported any major negative side effects, suggesting it is generally well-tolerated. Since this trial is in Phase 2, the treatment has already passed initial safety tests in earlier trials. This phase focuses more on the treatment's effectiveness, with ongoing safety checks.12345

Why are researchers excited about this trial?

Researchers are excited about the Tele-exercise for Brain Cancer Survivors trial because it explores a unique approach to recovery and quality of life improvements for young adults who have survived brain cancer. Unlike traditional rehabilitation options that might require in-person sessions, this trial involves a remote supervised exercise program, making it accessible for participants regardless of their location. The focus is on integrating regular exercise remotely, which could potentially enhance physical health, cognitive function, and emotional well-being from the comfort of home. This could be a game-changer in making rehabilitation more convenient and personalized for brain cancer survivors.

What evidence suggests that the RISE-YA intervention is effective for cancer-related fatigue in brain cancer survivors?

Research shows that the RISE-YA program, a virtual exercise routine done at home, might help young adults who have survived brain cancer become more active and think more clearly. In this trial, participants will divide into two groups: one will engage in the RISE-YA intervention, while the other will join an attention control group. Studies have found that exercise can improve physical abilities and mental well-being in cancer survivors. These benefits suggest that exercise might also reduce the fatigue often experienced by brain cancer survivors. While specific information on how RISE-YA affects fatigue is still being gathered, the overall benefits of exercise are well known. The program is based on evidence supporting exercise as a helpful way to manage and improve the quality of life for cancer survivors.12678

Who Is on the Research Team?

MR

Michael Roth, MD

Principal Investigator

M.D. Anderson Cancer Center

Are You a Good Fit for This Trial?

This trial is for young adult survivors of brain cancer who are experiencing fatigue related to their cancer. Specific eligibility criteria details were not provided, so interested individuals should contact the study organizers for more information.

Inclusion Criteria

Functional Assessment of Chronic Illness therapy (FACIT)-Fatigue score ≤ 43
Engages in <150 minutes of physical activity and <2 sessions of muscle strengthening exercise per week
Must be able to speak, write, and read English
See 6 more

Exclusion Criteria

Screen failure for exercise safety
Self-report of pregnancy
Prisoners
See 6 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants undergo the RISE-YA tele-exercise intervention to improve cancer-related fatigue

12 weeks
Weekly virtual sessions

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

Long-term follow-up

Monitoring of adverse events and other outcomes through study completion

1 year

What Are the Treatments Tested in This Trial?

Interventions

  • RISE-YA Intervention
Trial Overview The study is examining the effects of a program called RISE-YA on reducing cancer-related fatigue in these survivors. It may involve survivorship education and other supportive activities delivered through telehealth methods.
How Is the Trial Designed?
2Treatment groups
Experimental Treatment
Group I: InItervention Group: Remote Implementation of Supervised Exercise for Young AdultExperimental Treatment1 Intervention
Group II: Attention Control GroupExperimental Treatment1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

M.D. Anderson Cancer Center

Lead Sponsor

Trials
3,107
Recruited
1,813,000+

Cancer Prevention Research Institute of Texas

Collaborator

Trials
55
Recruited
98,900+

Citations

Virtual Home-based Exercise Intervention (RISE) to ...Participating in the virtual home-based exercise intervention, RISE, may improve physical activity and cognitive impairment in AYA brain tumor survivors and may ...
Virtual Home-based Exercise Intervention (RISE) to ...Participating in the virtual home-based exercise intervention, RISE, may improve physical activity and cognitive impairment in AYA brain tumor ...
Virtual Home-based Exercise Intervention (RISE) to Improve ...Participating in the virtual home-based exercise intervention, RISE, may improve physical activity and cognitive impairment in AYA brain tumor survivors and may ...
Cancer-related Fatigue and Its Biological Contributors in Adolescent ...The goal of this research study is to learn about the effects of the RISE-YA intervention on cancer-related fatigue in young adults who are brain cancer ...
Exercise Improves Physical Function and Mental Health of ...In summary, the outcomes from this report are intended to build a level of evidence regarding the benefits of exercise for cancer survivors with brain tumors.
Virtual Home-based Exercise Intervention (RISE) toThis clinical trial evaluates the impact of a research intervention of virtually supervised exercise program (RISE) on cancer-related cognitive impairment ...
Physical Activity Intervention Characteristics and Effects on ...Participation in physical activity (PA) during and after cancer treatment is safe and beneficial in the adolescent and young adult (AYA) cancer population.
A randomised controlled trial investigating the ability for ...Conclusions. This study demonstrated that the 10-week supervised exercise program (EG) resulted in superior strength and QOL outcomes in AYA ...
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