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GEN-1 + Chemo + Bevacizumab for Ovarian Cancer (MRD Trial)
MRD Trial Summary
This trial tests if adding a drug to chemo + Bev can better treat cancer.
MRD Trial Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowMRD Trial Timeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.MRD Trial Design
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Who is running the clinical trial?
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- I haven't had radiation in my abdomen or pelvis but may have had it for breast, head and neck, or skin cancer over three years ago without recurrence.I haven't had a serious illness, infection needing strong antibiotics, or COVID-19 in the last 4 weeks.I have previously been treated with IMNN-001.I haven't taken steroids in the last 2 weeks and don't need them for chronic conditions.I have a history of diverticulitis, but not just diverticulosis.I have a kidney condition with significant protein in my urine.I do not have HIV or HTLV infections.My ovarian cancer is a specific type called high grade serous adenocarcinoma.I haven't had any other cancer besides non-invasive types in the last 3 years.I haven't had chemotherapy for any abdominal or pelvic tumor, but I may have had it for breast cancer over three years ago without recurrence.I am suspected to have advanced ovarian, fallopian tube, or peritoneal cancer, awaiting confirmation via laparoscopy.My cancer is at an advanced stage and my doctor recommends starting treatment before surgery.My bone marrow, kidneys, liver, and nervous system are all functioning well.I stopped my cancer hormone therapy at least a week ago but may continue hormone replacement therapy.I have an autoimmune disease and have been on immunosuppressive therapy in the last 2 years.I don't have any health issues that would prevent safe placement of a catheter for treatment.I have no history of major brain-related health issues in the past 6 months.I am fully active or restricted in physically strenuous activity but can do light work.I have a serious heart condition.I have coughed up blood in the last month.I have active hepatitis.I am not pregnant, breastfeeding, and I use effective birth control.
- Group 1: Chemotherapy + BEV + IMNN-001 (Experimental)
- Group 2: Chemotherapy + BEV (Control)
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Does the FDA sanction combination treatment of Chemotherapy, BEV, and GEN-1?
"Safety ratings for the combination of Chemotherapy + BEV + GEN-1 (Experimental) were assessed at 2, as there was prior evidence backing its safety profile yet no data to support efficacy."
How many individuals have been recruited for this experiment?
"Affirmative. As per the clinicaltrials.gov page, this investigation is still recruiting individuals to take part in it. The trial was announced on February 10th 2023 and its details were most recently revised as of February 13th 2023. It seeks 50 participants at one medical facility."
Are there any opportunities left to enroll in this clinical experiment?
"As visible from the clinicaltrials.gov page, potential participants are being sought for this trial. This investigation was originally posted on February 10th, 2023 and recently updated on February 13th of that same year."
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