Image-Guided Radiation Therapy for Cervical Cancer
What You Need to Know Before You Apply
What is the purpose of this trial?
This is a research study using Granulocyte Colony Stimulating Factor (GCSF) as a bone marrow stimulating agent for imaging to guide radiation treatment planning. G-CSF is a type of growth factor. Growth factors are proteins made in the body. G-CSF is a type of growth factor that makes the bone marrow produce white blood cells to reduce the risk of infection after some types of cancer treatment. GCSF is being given to stimulate the bone marrow to identify the active (blood cell producing regions) to better spare during pelvic radiation treatment planning.
Do I need to stop my current medications for this trial?
The trial information does not specify whether you need to stop taking your current medications. It's best to discuss this with the trial coordinators or your doctor.
Is Image-Guided Radiation Therapy for Cervical Cancer using G-CSF treatments like Pegfilgrastim safe?
How does image-guided radiation therapy differ from other treatments for cervical cancer?
Image-guided radiation therapy for cervical cancer is unique because it uses advanced imaging techniques to precisely target the tumor, allowing for higher doses of radiation to be delivered directly to the cancer while minimizing damage to surrounding healthy organs. This approach improves pelvic control and survival rates compared to traditional radiation therapy.678910
What data supports the effectiveness of the drug G-CSF (Granulocyte Colony Stimulating Factor) in treating cervical cancer?
Who Is on the Research Team?
Elizabeth A Kidd, MD
Principal Investigator
Stanford Universiy
Are You a Good Fit for This Trial?
This trial is for individuals with certain stages of cervical or endometrial cancer who haven't had pelvic radiation, other cancer treatments in the past 2 years, or conditions preventing chemotherapy. They must have good kidney and bone marrow function, an ECOG performance status of 0-2, and be able to consent.Inclusion Criteria
Exclusion Criteria
Timeline for a Trial Participant
Screening
Participants are screened for eligibility to participate in the trial
Dose Finding
Phase I involves dose finding with GCSF in cohorts to determine the optimal dose for phase II
Treatment
Participants receive chemoradiation with GCSF at the optimal dose determined in phase I
Follow-up
Participants are monitored for safety and effectiveness after treatment
What Are the Treatments Tested in This Trial?
Interventions
- GCSF
Find a Clinic Near You
Who Is Running the Clinical Trial?
Stanford University
Lead Sponsor