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Image-Guided Radiation Therapy for Cervical Cancer
Study Summary
This trial is testing if G-CSF can help guide radiation therapy by making cancer cells more visible on imaging.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check βYesβ for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- I cannot undergo chemotherapy due to a medical condition.My blood tests show normal white cell and platelet counts.My kidney function is within the normal range.I can take care of myself and am up and about more than half of the day.I haven't had extensive radiation therapy in the abdominal area.I have had radiation therapy to my pelvic area before.You have received treatment for another type of cancer within the past two years.I have early to advanced cervical or endometrial cancer, with or without prior surgery.
- Group 1: Phase II-G-CSF
- Group 2: Phase I -Dose finding, Cohort 3
- Group 3: Phase I -Dose finding, Cohort 2
- Group 4: Phase I -Dose finding, Cohort 1
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
Are there any positions available for volunteers in this clinical trial?
"The study, which can be found on clinicaltrials.gov, is still recruiting patients. The start date for this research was February 1st, 2021 and the most recent update was on August 17th, 2022."
Could you explain the common reasons why doctors prescribe GCSF?
"GCSF is primarily used to treat febrile neutropenia. However, it can also be given to patients experiencing neutropenia, infection, or myeloablative chemotherapy in order to mitigate these conditions."
Can you tell me if there is a precedent for this type of therapy?
"Currently, 168 clinical trials that focus on GCSF are ongoing with 37 Phase 3 studies. The majority of these investigations into GCSF are being conducted in Saint Louis, Missouri; however, there are 4,670 total locations running clinical trials related to this medication."
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