Study Summary
This trialcompares how well different anesthetics reduce pain and opioid use after skin grafts for partial or full thickness burns.
- Postoperative Pain
- Burns
Treatment Effectiveness
Phase-Based Effectiveness
Study Objectives
1 Primary · 2 Secondary · Reporting Duration: Pain scores associated with skin graft donor site will be assessed using Visual Analog Scale (0-10) at 4,8, 12, 24, 48 and 72 hours after surgery. They will be compared between two groups.
Trial Safety
Phase-Based Safety
Awards & Highlights
Trial Design
3 Treatment Groups
Group 2
1 of 3
Group 3
1 of 3
Group 1
1 of 3
Active Control
Experimental Treatment
75 Total Participants · 3 Treatment Groups
Primary Treatment: Group 3 · No Placebo Group · Phase 4
Trial Logistics
Trial Timeline
Who is running the clinical trial?
Eligibility Criteria
Age 18+ · All Participants · 0 Total Inclusion Criteria
Mark “Yes” if the following statements are true for you:- Egan KG, Guest R, Sinik LM, Nazir N, De Ruyter M, Ponnuru S, Bhavsar D. Evaluation of Liposomal Bupivacaine at Split-Thickness Skin Graft Donor Sites Through a Randomized, Controlled Trial. J Burn Care Res. 2021 Nov 24;42(6):1280-1285. doi: 10.1093/jbcr/irab129.
- Dhaval Bhavsar 2019. "Liposomal Bupivacaine Versus Lidocaine for Skin Graft Donor Site Pain". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03854344.
Frequently Asked Questions
What primary ailments can Group 1 be applied to?
"Group 1 treatments are frequently used to treat minor burns, but they can also provide relief from lupus erythematosus cell, ulcerative colitis and transplantation." - Anonymous Online Contributor
What security measures can be taken to ensure Group 1 is not a hazard for people?
"As this is a phase 4 trial, which signals a treatment's approval, our team at Power gave Group 1 an assessment of 3 on the safety scale." - Anonymous Online Contributor
How many volunteers are currently partaking in this clinical experiment?
"Indeed. According to clinicaltrials.gov, this study posted on March 18th 2019 is still enrolling patients and was recently updated on December 28th 2022. 75 participants are needed at the single site hosting the trial." - Anonymous Online Contributor
Are there still open slots available for this research endeavor?
"Affirmative. Clinicaltrials.gov indicates that this investigation, which was published on March 18th 2019, is currently seeking participants. An estimated 75 people need to be enrolled from 1 center of care." - Anonymous Online Contributor
What further research has been conducted concerning Group 1?
"At present, 40 trials for Group 1 are in the third phase of development. Furthermore, 192 active studies exist within this group and 1203 locations across Germantown, Tennessee have been conducting these tests." - Anonymous Online Contributor