60 Participants NeededMy employer runs this trial

Icovamenib for Type 2 Diabetes

Recruiting at 14 trial locations
BF
Overseen ByBiomea Fusion Inc.
Age: 18+
Sex: Any
Trial Phase: Phase 2
Sponsor: Biomea Fusion Inc.
Must be taking: Antihyperglycemics
Prior Safety DataThis treatment has passed at least one previous human trial

What You Need to Know Before You Apply

What is the purpose of this trial?

This is a Phase 2, randomized, double-blind, placebo-controlled trial assessing the efficacy and safety of icovamenib in participants with Type 2 Diabetes who are not achieving glycemic targets despite antihyperglycemic medications.

Are You a Good Fit for This Trial?

Inclusion Criteria

I have been diagnosed with type 2 diabetes.
I have managed my diabetes with 1-3 stable medications for at least 3 months.
4. Have HbA1c ≥7.5 and ≤10.5%
See 4 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive icovamenib or placebo in addition to their current antihyperglycemic medications for 12 weeks

12 weeks
Regular visits for monitoring

Continuation

Participants continue on their currently prescribed antihyperglycemic medication(s) after the initial 12-week treatment phase

40 weeks

Follow-up

Participants are monitored for safety and effectiveness after treatment

4 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • Icovamenib

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Placebo Group

Group I: Arm A: icovamenib 100 mgExperimental Treatment1 Intervention
Group II: Arm B: matching placebo 100 mgPlacebo Group1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Biomea Fusion Inc.

Lead Sponsor

Trials
5
Recruited
780+