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Behavioural Intervention

Active transcutaneous spinal direct current stimulation for Depression (SPIDEP Trial)

Phase 1 & 2
Waitlist Available
Led By Francisco Romo-Nava, MD,PhD
Research Sponsored by University of Cincinnati
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 8 weeks
Awards & highlights

SPIDEP Trial Summary

This trial will test whether a non-invasive brain stimulation technique can help treat major depressive disorder.

Eligible Conditions
  • Depression

SPIDEP Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~8 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 8 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
MADRS score change
Secondary outcome measures
Adiponectin level change
Adverse Event frequency difference
Binge Eating Scale (BES) score change
+16 more
Other outcome measures
Emotion recognition task scores change (exploratory)
Stop signal task scores change (exploratory)

SPIDEP Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Active TreatmentExperimental Treatment1 Intervention
Thoracic anodal transcutaneous spinal direct current stimulation 2.5mA for 20 min/ three times per week for 8 weeks.
Group II: Sham TreatmentPlacebo Group1 Intervention
Thoracic anodal transcutaneous spinal direct current sham stimulation session of 20min/ three times per week for 8 weeks.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Active transcutaneous spinal direct current stimulation
2018
Completed Phase 2
~20

Find a Location

Who is running the clinical trial?

Brain & Behavior Research FoundationOTHER
61 Previous Clinical Trials
2,794 Total Patients Enrolled
19 Trials studying Depression
1,115 Patients Enrolled for Depression
University of CincinnatiLead Sponsor
428 Previous Clinical Trials
634,366 Total Patients Enrolled
21 Trials studying Depression
1,391 Patients Enrolled for Depression
Lindner Center of HOPEOTHER
28 Previous Clinical Trials
1,375 Total Patients Enrolled
5 Trials studying Depression
335 Patients Enrolled for Depression

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Spinal Cord Stimulation for the Treatment of Major Depressive Disorder
Francisco Romo-Nava 2018. "Spinal Cord Stimulation for the Treatment of Major Depressive Disorder". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03433339.
~3 spots leftby Apr 2025
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