Treatment for Depression

City Center Pharmacy and Medical Clinic, Edmonton, Canada
Depression
Eligibility
18 - 64
All Sexes

Study Summary

This trialtests whether adding almond therapy to esketamine can help people better than just esketamine alone.

Eligible Conditions
  • Treatment-Resistant Depression

Treatment Effectiveness

Study Objectives

1 Primary · 6 Secondary · Reporting Duration: Screening, Day 2, 5, 9, 12,16, ,19, 23, 26 and 28

Screening and Day 28
Change in EuroQol-5 Dimensional Questionnaire
Change in Post-traumatic Stress Disorder Checklist for Diagnostic and Statistical Manual of Mental Disorders (PCL-5)
Change in Quality of Life 8 Dimensional Questionnaire (AQoL-8D)
Change in Rosenberg Self-Esteem Questionnaire (RSES)
Day 2
Change in Generalized Anxiety Disorder Questionnaire (GAD-7)
Day 2
Change in Patient Health Questionnaire (PHQ-9)
Day 7
Change in the Montgomery Asberg Depression Rating Scale (MADRS) from screening to Day 28

Trial Safety

Phase-Based Safety

2 of 3
This is further along than 68% of similar trials

Awards & Highlights

No Placebo Group
All patients enrolled in this trial will receive the new treatment.

Trial Design

0 Treatment Group

6 Total Participants · 0 Treatment Group

Primary Treatment: Treatment · No Placebo Group · Phase 2

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: screening, day 2, 5, 9, 12,16, ,19, 23, 26 and 28

Who is running the clinical trial?

Zylorion HealthLead Sponsor
1 Previous Clinical Trials
1 Trials studying Depression
Pierre Chue, MBBChPrincipal InvestigatorAmygdala Associates
1 Previous Clinical Trials
1 Trials studying Depression

Eligibility Criteria

Age 18 - 64 · All Participants · 1 Total Inclusion Criteria

Mark “Yes” if the following statements are true for you:
If you are taking medication for depression, the dosage of your antidepressant must have remained the same for at least 4 weeks before the study begins.

Frequently Asked Questions

Is this research initiative currently looking for participants?

"Affirmative. Clinicaltrials.gov shows that this research, first posted on October 13th 2022, is presently looking for enrollees. 102 individuals must enroll at one medical centre to complete the trial." - Anonymous Online Contributor

Unverified Answer

What is the magnitude of participants in this clinical experiment?

"Affirmative. Entries on clinicaltrials.gov conclusively demonstrate that this investigation is currently seeking patients, having been initiated on October 13th 2022 and amended most recently on November 9th 2022. 102 individuals are required from a solitary medical centre for the trial to be completed successfully." - Anonymous Online Contributor

Unverified Answer

Who is eligible to participate in this research experiment?

"The prerequisites for this trial necessitate that applicants have a diagnosis of unipolar depression and be aged between 18 to 64. All told, 102 participants are required in order to complete the study." - Anonymous Online Contributor

Unverified Answer

Are the eligibility requirements of this trial inclusive to those aged 70 and above?

"The inclusion criteria for this trial necessitate that participants are aged 18 or more, yet less than 64 years of age." - Anonymous Online Contributor

Unverified Answer

How efficacious is this procedure for those under its care?

"Due to the Phase 2 status of this trial, there is partial evidence that suggests safety but no data available yet for efficacy. Therefore, our team rated the safety as a score of 2 on a 1-3 scale." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.