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Oral Rehydration Solution

Oral rehydration solution 1 for Hydration

Phase 1 & 2
Waitlist Available
Led By Craig A Horswill, PhD
Research Sponsored by University of Illinois at Chicago
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2 hours
Awards & highlights

Study Summary

The study examines interactions between fluid availability in the gut and fluid retention in the body. The relative rate of fluid uptake, the expansion of the plasma volume, and percent of fluid retained by the body will be measured in response to ingestion of beverages of different composition. Healthy, euhydrated adults will be studied. The results will help establish formulations of beverages that sustain if not promote acute euhydration.

Eligible Conditions
  • Hydration
  • Dehydration
  • Edema

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2 hours
This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 hours for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Rate of appearance of deuterium in the plasma for oral rehydration solution 1.
Rate of appearance of deuterium in the plasma for oral rehydration solution 2.
Rate of appearance of deuterium in the plasma for placebo
Secondary outcome measures
Change in plasma volume for oral rehydration solution 1
Change in plasma volume for oral rehydration solution 2
Change in plasma volume for placebo
+3 more

Trial Design

3Treatment groups
Experimental Treatment
Placebo Group
Group I: Oral rehydration solution 2Experimental Treatment1 Intervention
Beverage with 1.7% glucose with 60 mmol sodium/L.
Group II: Oral rehydration solution 1Experimental Treatment1 Intervention
Beverage with 2.5% glucose with 45 mmol sodium/L.
Group III: PlaceboPlacebo Group1 Intervention
Water
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Oral Rehydration Solution 2
2021
Completed Phase 2
~20
Oral Rehydration Solution 1
2021
Completed Phase 2
~20

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Logistics

Participation is compensated

You will be compensated for participating in this trial.

Who is running the clinical trial?

University of Illinois at ChicagoLead Sponsor
608 Previous Clinical Trials
1,559,235 Total Patients Enrolled
Craig A Horswill, PhDPrincipal InvestigatorUniversity of Illinois at Chicago
Craig Horswill, PhDPrincipal InvestigatorUniversity of Illinois at Chicago
1 Previous Clinical Trials
26 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Hydration Dynamics and Influence of Beverage Composition
Craig A. Horswill 2021. "Hydration Dynamics and Influence of Beverage Composition". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05111392.
~4 spots leftby Apr 2025
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