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Essential Oil

Peppermint Oil for Interstitial Cystitis

Phase 1 & 2
Recruiting
Led By Sean Francis, MD
Research Sponsored by University of Louisville
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 8 weeks
Awards & highlights

Study Summary

This trial will study whether peppermint oil can help treat IC/BPS.

Eligible Conditions
  • Interstitial Cystitis

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~8 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 8 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
O'Leary/Sant questionnaire scores
Pelvic Pain and Urgency/Frequency questionnaire scores
Secondary outcome measures
Additional IC/BPS Treatments received
Incidence of urinary tract infections (UTIs)
Urine pH

Side effects data

From 2015 Phase 2 trial • 8 Patients • NCT02291445
25%
Headache
25%
Altered Fecal Odor
100%
80%
60%
40%
20%
0%
Study treatment Arm
Ileocolonic Release PO
Small Intestinal Release PO

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Peppermint OilExperimental Treatment1 Intervention
Participants in the intervention (peppermint oil) arm will receive soft gels of enteric-coated peppermint oil (0.2mL=200mg). The enteric coated peppermint oil soft gel utilized in this study is Peptogest Peppermint Oil from Schwabe North America (Nature's Way Brand).
Group II: Coconut OilPlacebo Group1 Intervention
Participants in the placebo (coconut oil) arm will receive soft gels of enteric coated coconut oil. The enteric coated coconut oil soft gel utilized in this study is Coconut Oil from Schwabe North America (Nature's Way Brand).
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Peppermint oil
FDA approved

Find a Location

Logistics

Participation is compensated

You will be compensated for participating in this trial.

Who is running the clinical trial?

University of LouisvilleLead Sponsor
338 Previous Clinical Trials
75,884 Total Patients Enrolled
Integrative Therapeutics, Inc.Industry Sponsor
1 Previous Clinical Trials
257 Total Patients Enrolled
Sean Francis, MDPrincipal InvestigatorDepartment Chair

Media Library

Peppermint Oil (Essential Oil) Clinical Trial Eligibility Overview. Trial Name: NCT04845217 — Phase 1 & 2
Interstitial Cystitis Research Study Groups: Peppermint Oil, Coconut Oil
Interstitial Cystitis Clinical Trial 2023: Peppermint Oil Highlights & Side Effects. Trial Name: NCT04845217 — Phase 1 & 2
Peppermint Oil (Essential Oil) 2023 Treatment Timeline for Medical Study. Trial Name: NCT04845217 — Phase 1 & 2

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Would I qualify to partake in this experiment?

"Candidates that wish to partake in this medical trial must have cystitis and interstitial, as well as being between 18-65 years old. The total number of participants needed is 100."

Answered by AI

Could you please describe prior research surrounding the efficacy of Peppermint oil?

"At present, two trials are underway that evaluate the efficacy of Peppermint oil; however, neither is in its final phase. These studies can be found in Louisville and another unidentified centre."

Answered by AI

Is enrollment currently available for this investigation?

"Currently, the clinical trial is accepting applicants. The study was initially publicized on September 15th 2021 and has since been amended as recently as August 19th 2022."

Answered by AI

Is this experiment enrolling participants of advanced age?

"The eligibility parameters for this clinical trial dictate that prospective participants must be aged 18 or older and the maximum age is capped at 65."

Answered by AI

How many individuals are partaking in this investigation?

"Affirmative, the trial is still searching for enrollees. It was initially listed on September 15th 2021 and has been recently modified on August 19th 2022 with a targeted requirement of 100 participants at 1 location."

Answered by AI

To what ailments is Peppermint oil commonly prescribed?

"Peppermint oil has been known to provide relief for hair loss, muscle pain, and the common cold."

Answered by AI
~28 spots leftby Apr 2025