Treatment for Parkinson's Disease

Phase-Based Progress Estimates
University of Vermont Medical Center, Burlington, VTParkinson's Disease+1 More
All Sexes
What conditions do you have?

Study Summary

This trial studies if pyridostigmine can help with constipation in people with Parkinson's Disease, as constipation can severely impact quality of life.

Eligible Conditions
  • Parkinson's Disease
  • Constipation

Treatment Effectiveness

Study Objectives

1 Primary · 7 Secondary · Reporting Duration: 13-15 Weeks

13-15 Weeks
Number of adverse events and serious adverse events that occur during the trial
9-11 Weeks
Changes from Baseline to the End of Study Visit in Beck Depression Inventory-II (BDI-II)
Parkinson Disease
Movement Disorders
Changes from Baseline to the End of Study Visit in the MDS-Sponsored Revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS) Parts I-IV
Parkinson Disease

Trial Safety

Safety Progress

2 of 3
This is further along than 68% of similar trials

Trial Design

0 Treatment Group

16 Total Participants · 0 Treatment Group

Primary Treatment: Treatment · No Placebo Group · Phase 2

Trial Logistics

Trial Timeline

Screening: ~3 weeks
Treatment: Varies
Reporting: 13-15 weeks

Who is running the clinical trial?

University of Vermont Medical CenterLead Sponsor
39 Previous Clinical Trials
25,645 Total Patients Enrolled
Lisa M Deuel, MDPrincipal InvestigatorUniversity of Vermont

Eligibility Criteria

Age 18+ · All Participants · 8 Total Inclusion Criteria

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Frequently Asked Questions

How does this treatment rate in terms of its impact on the long-term health and wellbeing of those who receive it?

"This Phase 2 trial has some evidence of safety, so our team at Power assigned it a score of 2. Unfortunately, there is currently no data confirming its efficacy." - Anonymous Online Contributor

Unverified Answer

What is the maximum participant capacity for this clinical research endeavor?

"Affirmative. confirms that this research is currently recruiting participants, having been first published on August 10th 2022 and updated most recently in October 2021. 16 individuals need to be recruited from 1 medical centre for the trial to continue." - Anonymous Online Contributor

Unverified Answer

Does this medical experiment have open enrollment at the moment?

"Confirmed. contains data which suggests that this experiment is currently recruiting and began on August 10th 2022. The latest update was October 31st 2022, with a total 16 participants needed from one medical centre alone." - Anonymous Online Contributor

Unverified Answer
Please Note: These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.