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Pyridostigmine for Parkinson's Disease
Study Summary
This trial studies if pyridostigmine can help with constipation in people with Parkinson's Disease, as constipation can severely impact quality of life.
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Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Side effects data
From 2016 Phase 4 trial • 87 Patients • NCT02308124Trial Design
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- I have been diagnosed with parkinsonism caused by medication.I have had surgery on my intestines before.I have been diagnosed with vascular parkinsonism.I agree to use effective birth control methods during and after the study.I have been diagnosed with a rare form of Parkinson's disease.I have severe asthma or COPD.I have had a blockage in my bladder or intestines.I can take pills by mouth.I am 18 years old or older.I have used pyridostigmine in the last 90 days.I am using two effective birth control methods during and 28 days after the study.I have been diagnosed with Parkinson's disease according to specific criteria.I don't have conditions that could be confused with Parkinson's or affect my eligibility.I have had constipation symptoms for over 3 months, with less than 3 bowel movements a week.
- Group 1: Pyridostigmine Bromide
- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
How does this treatment rate in terms of its impact on the long-term health and wellbeing of those who receive it?
"This Phase 2 trial has some evidence of safety, so our team at Power assigned it a score of 2. Unfortunately, there is currently no data confirming its efficacy."
What is the maximum participant capacity for this clinical research endeavor?
"Affirmative. Clinicaltrials.gov confirms that this research is currently recruiting participants, having been first published on August 10th 2022 and updated most recently in October 2021. 16 individuals need to be recruited from 1 medical centre for the trial to continue."
Does this medical experiment have open enrollment at the moment?
"Confirmed. Clinicaltrials.gov contains data which suggests that this experiment is currently recruiting and began on August 10th 2022. The latest update was October 31st 2022, with a total 16 participants needed from one medical centre alone."
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