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Single-Sprint Training for Cardiovascular Health (VASST Trial)

Phase 2
Recruiting
Research Sponsored by University of Mississippi, Oxford
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up week 0, week 2, and week 4
Awards & highlights

VASST Trial Summary

This trial will assess if a single sprint exercise intervention can improve cardiovascular, microvascular and fitness functions in 40 males and females.

Who is the study for?
This trial is for healthy, untrained individuals aged 18-35 who haven't exercised regularly in the past 6 months. They must be able to start exercising safely. People taking blood pressure or heart rate medication, those with illnesses or injuries preventing cycling exercise, and recent nicotine users cannot participate.Check my eligibility
What is being tested?
The study tests if single-sprint training on a cycle ergometer improves vascular function and cardiorespiratory fitness. Participants are randomly assigned to either sprint training three times a week for four weeks or a control group maintaining their usual habits.See study design
What are the potential side effects?
Since this intervention involves physical exercise, potential side effects may include muscle soreness, fatigue, and an increased risk of injury during activity. However, these are common reactions to starting an exercise routine.

VASST Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~week 0, week 2, and week 4
This trial's timeline: 3 weeks for screening, Varies for treatment, and week 0, week 2, and week 4 for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change from baseline local and systemic microvascular function at 2 weeks and 4 weeks
Change from baseline systemic macrovascular function at 2 weeks and 4 weeks
Secondary outcome measures
Change from baseline maximal oxygen consumption at 2 weeks and 4 weeks

VASST Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: InterventionExperimental Treatment1 Intervention
The intervention group will perform a single maximal effort sprint on a cycle ergometer for twenty seconds 3 days/week for 4 weeks.
Group II: Time-Matched ControlActive Control1 Intervention
The control group will be asked to maintain pre-intervention habits/behavior over 4 weeks.

Find a Location

Who is running the clinical trial?

University of Mississippi, OxfordLead Sponsor
11 Previous Clinical Trials
952 Total Patients Enrolled

Media Library

Single-Sprint Training Clinical Trial Eligibility Overview. Trial Name: NCT05727332 — Phase 2
Cardiovascular Research Study Groups: Time-Matched Control, Intervention
Cardiovascular Clinical Trial 2023: Single-Sprint Training Highlights & Side Effects. Trial Name: NCT05727332 — Phase 2
Single-Sprint Training 2023 Treatment Timeline for Medical Study. Trial Name: NCT05727332 — Phase 2

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this scientific research involve individuals over the age of thirty?

"This research is looking for participants who are within the age bracket between 18 and 35 years old."

Answered by AI

Is there an opportunity for me to participate in this research trial?

"Candidates who will be accepted into this medical study must possess cardiovascular health and are limited to between 18 and 35 years of age. Altogether, 40 participants will be enrolled in the trial."

Answered by AI

Does this Intervention have official sanction from the Food and Drug Administration?

"Our analysis at Power rated the safety of Intervention to be a 2 as there is some evidence for its security, but no research has been conducted that confirms its effectiveness."

Answered by AI

Are new participants being accepted for this clinical exploration?

"Per the clinicaltrials.gov database, this medical research is not currently recruiting participants; it was originally posted on March 1st 2023 and last updated February 3rd 2023. Nevertheless, two other studies are presently enrolling patients in need of treatment."

Answered by AI
~4 spots leftby Jun 2024