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Radiation

Partial Breast IMRT for Early Stage Breast Cancer

Phase 1 & 2

Waitlist Available

Led By Ruth Heimann, M.D., Ph.D.

Research Sponsored by University of Vermont

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Age over 65

Stage I ductal breast cancer

Timeline

Screening 3 weeks

Treatment Varies

Follow Up up to 5 years

Awards & highlights

Study Summary

This trial is studying a shorter, more intense radiation therapy for early stage breast cancer.

Who is the study for?

This trial is for women over 65 with Stage I ductal breast cancer who've had a lumpectomy and no lymphovascular invasion. They should have clear surgical margins, visible lumpectomy cavity on CT, and be able to start radiation within 3-8 weeks post-surgery.Check my eligibility

What is being tested?

The study tests if high-dose daily radiation for a shorter period (10 treatments) using IMRT technology can effectively treat breast cancer with fewer side effects compared to the standard longer treatment duration (28-33 treatments).See study design

What are the potential side effects?

Potential side effects include skin changes, fatigue, pain or discomfort in the treated area. Long-term risks may involve changes in breast appearance or texture. The use of IMRT aims to minimize these side effects.

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

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I am over 65 years old.

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My breast cancer is in the early stage (Stage I).

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I am female.

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I have had a lumpectomy or partial mastectomy and lymph node removal.

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My lumpectomy cavity can be seen on a CT scan.

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ up to 5 years

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~up to 5 years

This trial's timeline: 3 weeks for screening, Varies for treatment, and up to 5 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Acute sdie effects

Percent of times that the target definition on planning CT is attained

Percent of times that the treatment is within the prescription goals

Secondary outcome measures

Cosmetic outcome

Percent experiencing local failure, time to recurrence and percent who can be retreated with radiation following recurrence

Set up variations

+1 more

0 / 5Eligibility criteria met

Find a Location

Who is running the clinical trial?

University of VermontLead Sponsor

266 Previous Clinical Trials

3,743,616 Total Patients Enrolled

10 Trials studying Breast Cancer

3,687,365 Patients Enrolled for Breast Cancer

Ruth Heimann, M.D., Ph.D.Principal InvestigatorUniversity of Vermont

Media Library

Partial Breast Radiation to the Lumpectomy Cavity with IMRT (Radiation) Clinical Trial Eligibility Overview. Trial Name: NCT00337064 — Phase 1 & 2

Breast Cancer Clinical Trial 2023: Partial Breast Radiation to the Lumpectomy Cavity with IMRT Highlights & Side Effects. Trial Name: NCT00337064 — Phase 1 & 2

Partial Breast Radiation to the Lumpectomy Cavity with IMRT (Radiation) 2023 Treatment Timeline for Medical Study. Trial Name: NCT00337064 — Phase 1 & 2

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Does this research project only include young adults as participants?

"This study is only open to patients who are 65 years or younger. Out of the 2754 clinical trials, this is one of only 65 that focus on this age group."

Answered by AI

Are there any open positions for volunteers in this experiment?

"Unfortunately, this particular clinical trial is not enrolling patients at the moment. The posting went up on June 1st 2006 and was edited last on June 13th of the same year. There are 2373 other trials that potential participants can look into though."

Answered by AI

Could I possibly be a candidate for this research?

"Researchers are looking for 75 geriatric patients with a recent breast cancer diagnosis to participate. All participants must be able to begin radiation therapy 3-8 weeks post surgery (unless they are receiving chemotherapy), have pathologically negative margins, and be female."

Answered by AI

Recent research and studies

clinicaltrials.govStudy

Partial Breast Radiation to the Lumpectomy Cavity With IMRT in Elderly Women

2006. "Partial Breast Radiation to the Lumpectomy Cavity With IMRT in Elderly Women". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT00337064.

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