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Inhaled Corticosteroids for Asthma
Phase 1 & 2
Waitlist Available
Led By Michelle Zeidler, MD
Research Sponsored by University of California, Los Angeles
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Mild to moderate persistent asthma (forced expiratory volume in 1 second [FEV1] greater than or equal to 70% predicted; PC20 less than or equal to 8 mg/ml) and currently using only short acting inhaled beta agonists as needed for control of asthma symptoms.
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to 5 years
Awards & highlights
Study Summary
This trial will help researchers understand if inflammation in the small airways is linked to asthma, and if so, if it can be treated with inhaled corticosteroids.
Who is the study for?
This trial is for adults aged 18 to 50 with mild to moderate persistent asthma, not using steroids or other excluded medications, and non-smokers for at least a year. Pregnant or breastfeeding women are ineligible, as well as those unwilling to prevent pregnancy during the study.Check my eligibility
What is being tested?
The study tests two types of inhaled corticosteroids on asthmatics: Flunisolide-CFC with large particles for central lung inflammation, and Flunisolide-HFA with small particles targeting both central and peripheral lung areas. The effectiveness will be measured through various lung function tests.See study design
What are the potential side effects?
Potential side effects include irritation from inhalers, discomfort from lung function testing procedures like bronchoscopy and HRCT scans. There may also be risks associated with taking corticosteroids such as throat irritation or fungal infections.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I have asthma that's not severe, and I only use quick-relief inhalers.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ up to 5 years
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to 5 years
Treatment Details
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Logistics
Participation is compensated
You will be compensated for participating in this trial.
Who is running the clinical trial?
University of California, Los AngelesLead Sponsor
1,528 Previous Clinical Trials
10,276,851 Total Patients Enrolled
3 Trials studying Asthma
94 Patients Enrolled for Asthma
Michelle Zeidler, MDPrincipal InvestigatorUniversity of California, Los Angeles
1 Previous Clinical Trials
34 Total Patients Enrolled
1 Trials studying Asthma
34 Patients Enrolled for Asthma
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- I am between 18 and 50 years old.I have asthma that's not severe, and I only use quick-relief inhalers.
Research Study Groups:
This trial has the following groups:Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Is there an age limit for participating in this scientific research?
"As indicated by the entry requirements, those wishing to join this experiment must be aged 18 or over and not exceed 50 years of age."
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