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Other

2 for Tobacco Use Disorder

Phase 2 & 3
Waitlist Available
Led By Marc E Mooney, Ph.D.
Research Sponsored by University of Minnesota
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up weekly during treatment
Awards & highlights

Study Summary

The purpose of this study is to compare the effects of bupropion + placebo to bupropion + naltrexone as treatments to help smokers quit.

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~7, 11, 16, and 30 weeks post-quit
This trial's timeline: 3 weeks for screening, Varies for treatment, and 7, 11, 16, and 30 weeks post-quit for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Biochemically-verified point-prevalence abstinence
Daily cigarette smoking rate.
Frequency and severity of bupropion and naltrexone side effects.
+2 more
Secondary outcome measures
Attentional bias.
Impulsivity.
Nicotine withdrawal, craving and negative/positive affect.

Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: 2Experimental Treatment1 Intervention
Bupropion+Naltrexone
Group II: 1Active Control1 Intervention
Bupropion+Placebo

Find a Location

Who is running the clinical trial?

National Institute on Drug Abuse (NIDA)NIH
2,464 Previous Clinical Trials
2,618,473 Total Patients Enrolled
271 Trials studying Tobacco Use Disorder
48,947 Patients Enrolled for Tobacco Use Disorder
University of MinnesotaLead Sponsor
1,377 Previous Clinical Trials
1,588,176 Total Patients Enrolled
42 Trials studying Tobacco Use Disorder
7,941 Patients Enrolled for Tobacco Use Disorder
Marc E Mooney, Ph.D.Principal InvestigatorUniverisity of Minnesota
3 Previous Clinical Trials
171 Total Patients Enrolled
2 Trials studying Tobacco Use Disorder
128 Patients Enrolled for Tobacco Use Disorder

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Study of Bupropion Versus Bupropion + Naltrexone for Smoking Cessation
2006. "Study of Bupropion Versus Bupropion + Naltrexone for Smoking Cessation". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT00419731.
All > Smoking > Smoking Cessation
~7 spots leftby Apr 2025
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