← Back to Search

Antifibrinolytic Agent

Tranexamic acid for Postoperative Hemorrhage

Phase 2 & 3
Recruiting
Research Sponsored by Ascension Health
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
1. All adult (18 years old or older) hip fracture patients presenting with an acute hip fracture and undergoing operative fixation
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up up to two weeks
Awards & highlights

Study Summary

This study is evaluating whether a drug called tranexamic acid can reduce blood loss in hip fractures.

Eligible Conditions
  • Postoperative Hemorrhage

Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~up to two weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and up to two weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Overall Blood Loss
Postoperative Blood Transfusion
Secondary outcome measures
Acute DVT/PE
Length of hospital stay
Pain
+1 more

Side effects data

From 2012 Phase 4 trial • 100 Patients • NCT00740116
22%
Readmissions
14%
Postoperative infections
10%
Re-operations
4%
Thromboembolic events
100%
80%
60%
40%
20%
0%
Study treatment Arm
Placebo Group
Tranexamic Group

Trial Design

2Treatment groups
Experimental Treatment
Group I: Intraoperative only TXAExperimental Treatment1 Intervention
This group will only receive the intraoperative TXA.
Group II: Early Adminstration of TXA + Intraoperative TXAExperimental Treatment1 Intervention
This group receives 1 G of TXA as soon as possible after a diagnosis of an acute hip fracture if the patient meets inclusion and exclusion criteria. The group will also receive 2 grams of TXA total intraoperatively.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Tranexamic acid
FDA approved

Find a Location

Who is running the clinical trial?

Ascension HealthLead Sponsor
25 Previous Clinical Trials
2,916 Total Patients Enrolled
Ascension Genesys HospitalLead Sponsor
18 Previous Clinical Trials
2,098 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Effect of Early Administration of TXA in Adult Hip Fractures
Jacob Hinkley 2021. "Effect of Early Administration of TXA in Adult Hip Fractures". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05047133.
~47 spots leftby Apr 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top