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Adderall XR for Cognitive Impairment in MS
Study Summary
This trial will compare the effects of two doses of Adderall XR (a mixed amphetamine salt, extended release medication) to placebo on measures of processing speed and memory in people with MS.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowTimeline
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Trial Design
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Who is running the clinical trial?
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- My blood pressure is not stable and often above 135/85 mmHg.I have a history of heart disease, such as blocked arteries or chest pain.I have hyperthyroidism or glaucoma.My medications have been the same for the last 30 days and won't change during the study.I am between 18 and 59 years old.I haven't taken corticosteroids or had a relapse in the last 90 days.I can walk with assistance.I am not pregnant or breastfeeding.I have a medical condition like ADHD or Alzheimer's that could affect my thinking.I have been diagnosed with bipolar disorder or have had a psychotic episode.I use marijuana more than three times a week or fourteen times a month.I am not taking any drugs that could interfere with the study medication.I am allergic to amphetamines or Adderall XR.I have kidney problems or am taking medication that could harm my kidneys.My family has a history of sudden death or heart rhythm issues.I have been diagnosed with multiple sclerosis according to the 2010 criteria.I agree to use birth control during and after the trial unless I am unable to have children.I am currently taking amphetamine or similar medications.I can see well enough with both eyes to take tests, even if I need glasses.
- Group 1: Placebo
- Group 2: Adderall XR 20mg
- Group 3: Adderall XR 10mg
- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
To what purpose is Adderall XR 20mg typically given to patients?
"Adderall XR 20mg can help patients effectively manage symptoms associated with disease, pain, and attention deficit hyperactivity disorder."
For which patients is this particular clinical trial designed?
"This trial is only for patients with multiple sclerosis aged 18-59. Around 180 people are needed for the study."
Could you please tell me if the age limit for participants in this trial is 30 years or older?
"Those who meet the age criteria of 18-59 years old are eligible for enrollment in this trial."
To what extent has Adderall XR 20mg been researched in other scientific papers?
"Out of the 12 ongoing studies investigating Adderall XR 20mg, 2 are in Phase 3. Additionally, these clinical trials for Adderall XR 20mg are not limited to Lexington, Kentucky as there are a total of 17 locations across the United States."
At how many different research sites can people participate in this trial?
"Currently, this trial is enrolling patients at 4 sites. The locations are situated in Toronto, Edmonton, London and other metropolitan areas. If you choose to enroll in the study, it is best to select the clinic closest to your residence to minimize travel requirements."
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