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Manual Therapy Plus Pulmonary Rehabilitation for Chronic Obstructive Pulmonary Disease

Phase 2 & 3
Waitlist Available
Led By Paul E Dougherty, DC
Research Sponsored by Canandaigua VA Medical Center
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up change from baseline to post intervention (4 weeks post baseline)
Awards & highlights

Study Summary

This trial will test if a combination of two different treatments can help improve COPD symptoms for Veterans.

Eligible Conditions
  • Chronic Obstructive Pulmonary Disease (COPD)

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~change from baseline to post intervention (4 weeks post baseline)
This trial's timeline: 3 weeks for screening, Varies for treatment, and change from baseline to post intervention (4 weeks post baseline) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Spirometry
Secondary outcome measures
6 Minute Walking Test (6MWT)
Hospital Anxiety and Depression scale: HAD
St Georges Respiratory Questionnaire: SGRQ

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: Manual therapy plus Pulmonary Rehabilitation (CMT+Experimental Treatment1 Intervention
Manual therapy is made up of gentle Effleurage and cross-fibre friction massage applied to the muscles of the posterior chest wall. Manual Therapy consists of two separate manipulations (Grade V mobilization). Each manipulation involves the delivery of a high-velocity low amplitude (HVLA) posterior to anterior force directed at the inter-vertebral, costo-vertebral and costo-transverse joints. The first manipulation is delivered at the level of the upper/middle thoracic spine while the second is at the level of the middle/lower thoracic spine. In addition to the MT, the participant will also undergo Pulmonary Rehab as previously described.
Group II: 'Sham' manual therapy plus Pulmonary Rehabilitation (PR)Placebo Group1 Intervention
Treadmill walking, upper body exercise machine, light weight training and bicycle. These exercises are supervised. In addition to the standard exercise therapy, all participants will undergo a 20-minute session consisting of discussion with the patient and 11 minutes of detuned ultrasound, which has been used in previous studies to account for time and attention for the patient. The detuned ultrasound procedure is to apply the ultrasound gel and turn the machine on, but set the intensity at zero (0) W/cm2

Find a Location

Who is running the clinical trial?

Canandaigua VA Medical CenterLead Sponsor
12 Previous Clinical Trials
1,826 Total Patients Enrolled
Paul E Dougherty, DCPrincipal InvestigatorVA Finger Lakes Healthcare System
2 Previous Clinical Trials
66 Total Patients Enrolled

Media Library

Manual Therapy Plus Pulmonary Rehabilitation Clinical Trial Eligibility Overview. Trial Name: NCT04386590 — Phase 2 & 3
Chronic Obstructive Pulmonary Disease Research Study Groups: 'Sham' manual therapy plus Pulmonary Rehabilitation (PR), Manual therapy plus Pulmonary Rehabilitation (CMT+
Chronic Obstructive Pulmonary Disease Clinical Trial 2023: Manual Therapy Plus Pulmonary Rehabilitation Highlights & Side Effects. Trial Name: NCT04386590 — Phase 2 & 3
Manual Therapy Plus Pulmonary Rehabilitation 2023 Treatment Timeline for Medical Study. Trial Name: NCT04386590 — Phase 2 & 3

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are there still opportunities for people to join this trial as participants?

"The most recent information on clinicaltrials.gov indicates that this study is still looking for patients and has not yet reached its 20 person goal. The trial was first posted on 6/15/2022 and was last edited on 3/29/2022."

Answered by AI

Are geriatric patients being accepted into this research program?

"This research study is only recruiting participants that are between the ages of 50 and 70, as noted in the inclusion criteria."

Answered by AI

How many study subjects are you working with presently?

"That is correct, the trial is still recruiting patients. The listing on clinicaltrials.gov shows that the study was first posted on June 15th, 2022 and updated most recently on March 29th, 2022. There is 1 location enrolling a maximum of 20 participants."

Answered by AI

Is this a study that only people with a certain medical condition can participate in?

"This clinical trial is enrolling 20 patients, between the ages of 50 and 70 who have lung diseases. It is important that participants also meet the following criteria: Sex: Male and Female, Age range: 50-70 years, Disease status: Moderate COPD (FEV1% predicted: moderate 50-80% (GOLD 2018)), Concomitant disease status: Stable COPD (no exacerbations in preceding 6 months) Non-smoking (for preceding 6 months), Willingness to give written informed consent., Willingness to participate in and comply with the study requirements.."

Answered by AI

Who else is applying?

What state do they live in?
Tennessee
How old are they?
18 - 65
What portion of applicants met pre-screening criteria?
Did not meet criteria
Recent research and studies
clinicaltrials.govStudy
Manual Therapy in Addition to Pulmonary Rehabilitation in Moderate Chronic Obstructive Pulmonary Disease.
Paul Dougherty, DC 2022. "Manual Therapy in Addition to Pulmonary Rehabilitation in Moderate Chronic Obstructive Pulmonary Disease.". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04386590.
All > Copd
~7 spots leftby Apr 2025
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