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Proton Pump Inhibitor

Esomeprazole for Acid Reflux (ISS Trial)

Phase 2 & 3
Waitlist Available
Led By Ronnie Fass, MD
Research Sponsored by Southern Arizona VA Health Care System
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 2 years
Awards & highlights

ISS Trial Summary

The purpose of this study is to determine if esomeprazole 40 mg. once daily improves not only nighttime symptoms but also significantly reduces conscious awakenings associated with gastroesophageal reflux and consequently improves sleep quality.

Eligible Conditions
  • Acid Reflux

ISS Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~2 years
This trial's timeline: 3 weeks for screening, Varies for treatment, and 2 years for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
The Effect of Esomeprazole 40 mg. Daily for 7 Days on Acid Reflux and Related Arousals During Sleep in Patients w/ GERD.

ISS Trial Design

1Treatment groups
Experimental Treatment
Group I: EsomeprazoleExperimental Treatment2 Interventions
Effect of PPI esomeprazole on acid reflux & related arousals during sleep in patients with GERD.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Esomeprazole
FDA approved
Esomeprazole
FDA approved

Find a Location

Who is running the clinical trial?

Southern Arizona VA Health Care SystemLead Sponsor
10 Previous Clinical Trials
888 Total Patients Enrolled
Ronnie Fass, MDPrincipal InvestigatorSAVAHCS
10 Previous Clinical Trials
399 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Recent research and studies
clinicaltrials.govStudy
Effect of Esomeprazole 40 mg.Daily for 7 Days on Acid Reflux and Related Arousals During Sleep in Patients With GERD
2010. "Effect of Esomeprazole 40 mg.Daily for 7 Days on Acid Reflux and Related Arousals During Sleep in Patients With GERD". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT01089959.
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