← Back to Search

Corticosteroid

Methylprednisolone Tablet for Hand Injuries

Phase 2 & 3

Waitlist Available

Led By Brian Katt, MD

Research Sponsored by Robert Wood Johnson Barnabas Health

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 12 weeks

Awards & highlights

Study Summary

This trial will test the efficacy of steroids in reducing pain and swelling, and improving range of motion and function, in patients with musculoskeletal injuries of the hand.

Eligible Conditions

Hand Injuries
Finger Injuries

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 12 weeks

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~12 weeks

This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

MCP, DIP, PIP of digits 2-5: Extension

MCP, DIP, PIP of digits 2-5: Flexion

MCP, DIP, PIP of digits 2-5: abduction

+11 more

Secondary outcome measures

Complications

Edema Measurements

VAS Pain Scale

Trial Design

2Treatment groups

Experimental Treatment

Active Control

Group I: Steroid GroupExperimental Treatment1 Intervention

Patients receive 21 tablets of 4 mg methylprednisolone to be taken by mouth over a 6 week taper. Patients will be advised to not take other anti-inflammatory medications like NSAIDs.

Group II: Control GroupActive Control1 Intervention

Patients will recieve standard treatment that focuses on mobilization and stabilization using common techniques like buddy taping and splinting. Pain control will be managed using non-NSAID medications like Tylenol or opioid narcotics when deemed medically necessary.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Methylprednisolone

FDA approved

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

Robert Wood Johnson Barnabas HealthLead Sponsor

1 Previous Clinical Trials

32 Total Patients Enrolled

Brielle OrthopedicsUNKNOWN

1 Previous Clinical Trials

32 Total Patients Enrolled

University Orthopedics AssociatesUNKNOWN

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How is Methylprednisolone Tablet typically employed?

"Methylprednisolone Tablet can be used to improve scalp structure, fight multiple sclerosis, and manage ulcerative colitis."

Answered by AI

Are patients being signed up for this clinical trial at this time?

"Unfortunately, this trial is no longer seeking participants. It was originally posted on September 1st, 2021 but was last updated on August 5th, 2021. There are currently 763 trials actively admitting participants with finger injuries and 155 trials for Methylprednisolone Tablet enrolling participants."

Answered by AI

Are there any other similar Methylprednisolone Tablet studies that have been completed?

"As of now, there are 155 active trials researching Methylprednisolone Tablet with 42 trials in Phase 3. While the majority of the studies for Methylprednisolone Tablet are based in Duarte, California, there are 6734 locations around the world operating trials for Methylprednisolone Tablet."

Answered by AI

Recent research and studies

Knee Surgery, Sports Traumatology, ArthroscopyJournal

Methylprednisolone Reduces Pain and Decreases Knee Swelling in the First 24 H After Fast-track Unicompartmental Knee Arthroplasty

Rytter, Søren, Maiken Stilling, Stig Munk, and Torben Bæk Hansen. 2015. “Methylprednisolone Reduces Pain and Decreases Knee Swelling in the First 24 H After Fast-track Unicompartmental Knee Arthroplasty”. Knee Surgery, Sports Traumatology, Arthroscopy. Springer Science and Business Media LLC. doi:10.1007/s00167-014-3501-8.

BMC Musculoskeletal DisordersJournal

Association of Wrist and Forearm Range of Motion Measures with Self-reported Functional Scores Amongst Patients with Distal Radius Fractures: A Longitudinal Study

Yang, Zixian, Peggy Poh Hoon Lim, Sing Hwee Teo, Huiwen Chen, Huaying Qiu, and Yong Hao Pua. 2018. “Association of Wrist and Forearm Range of Motion Measures with Self-reported Functional Scores Amongst Patients with Distal Radius Fractures: A Longitudinal Study”. BMC Musculoskeletal Disorders. Springer Science and Business Media LLC. doi:10.1186/s12891-018-2065-z.

Journal of Oral and Maxillofacial SurgeryJournal

Comparison of Nonsteroidal Anti-inflammatory Drugs, Ibuprofen and Flurbiprofen, with Methylprednisolone and Placebo for Acute Pain, Swelling, and Trismus

Troullos, Emanuel S., Kenneth M. Hargreaves, Donald P. Butler, and Raymond A. Dionne. 1990. “Comparison of Nonsteroidal Anti-inflammatory Drugs, Ibuprofen and Flurbiprofen, with Methylprednisolone and Placebo for Acute Pain, Swelling, and Trismus”. Journal of Oral and Maxillofacial Surgery. Elsevier BV. doi:10.1016/0278-2391(90)90007-o.

Basic & Clinical Pharmacology & ToxicologyJournal