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ALY688 Ophthalmic Solution for Dry Eye Syndrome (OASIS-1 Trial)

Phase 2 & 3
Waitlist Available
Research Sponsored by Allysta Pharmaceutical
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 8 weeks
Awards & highlights

OASIS-1 Trial Summary

This study is evaluating whether a new eye drop may help improve dry eye disease.

Eligible Conditions
  • Dry Eye Syndrome

OASIS-1 Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~8 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 8 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Corneal fluorescein staining

Side effects data

From 2015 Phase 4 trial • 157 Patients • NCT02003391
6%
Ocular hyperaemia
5%
Eye pruritus
2%
Nasopharyngitis
2%
Dry eye
1%
Acute tonsillitis
1%
Pharyngitis
1%
Conjunctivitis allergic
1%
Eyelids pruritus
1%
Blepharal pigmentation
1%
Eye irritation
1%
Cataract
1%
Arthritis
1%
Hypersensitivity
1%
Eye pain
1%
Ocular surface disease
100%
80%
60%
40%
20%
0%
Study treatment Arm
DuoTrav
Beta-blocker

OASIS-1 Trial Design

3Treatment groups
Experimental Treatment
Placebo Group
Group I: ALY688 Ophthalmic Solution Concentration 2Experimental Treatment1 Intervention
Group II: ALY688 Ophthalmic Solution Concentration 1Experimental Treatment1 Intervention
Group III: Vehicle Ophthalmic SolutionPlacebo Group1 Intervention
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
ALY688 Ophthalmic Solution
2021
Completed Phase 3
~930

Find a Location

Who is running the clinical trial?

Allysta PharmaceuticalLead Sponsor
3 Previous Clinical Trials
233 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are we still recruiting individuals for this research project?

"According to information found on clinicaltrials.gov, this study is not currently recruiting patients for participation. The trial was first posted on May 19th, 2021 and the most recent update was on November 8th, 2022. Although this particular study is not looking for volunteers at the moment, there are 150 other studies that are actively seeking participants right now."

Answered by AI
Recent research and studies
clinicaltrials.govStudy
ALY688 Ophthalmic Solution in Subjects With Dry Eye Disease
2021. "ALY688 Ophthalmic Solution in Subjects With Dry Eye Disease". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT04899518.
~235 spots leftby May 2025
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