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Rimegepant for Temporomandibular Joint Disorder

Phase 3
Waitlist Available
Research Sponsored by Biohaven Pharmaceuticals, Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up number of minutes post dose in which pain decreases by 30%
Awards & highlights

Study Summary

This trial will compare the effectiveness of a new drug, rimegepant, to a placebo in treating Temporomandibular Disorders, which involve the jawbone joint and surrounding muscles.

Eligible Conditions
  • Temporomandibular Joint Disorder (TMJ Disorder)

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~number of minutes post dose in which pain decreases by 30%
This trial's timeline: 3 weeks for screening, Varies for treatment, and number of minutes post dose in which pain decreases by 30% for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
To evaluate the efficacy of rimegepant compared with placebo in the acute treatment of Temporomandibular Disorders
Secondary outcome measures
To evaluate rimegepant compared to placebo on change from baseline of pain
To evaluate rimegepant compared to placebo on the probability of requiring rescue medication
To evaluate rimegepant compared to placebo on the proportion of subjects that are pain free
+3 more

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: BHV3000 (rimegepant)Experimental Treatment1 Intervention
One dose of rimegepant 75 mg ODT
Group II: Matching PlaceboPlacebo Group1 Intervention
One dose of matching placebo
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Rimegepant
2021
Completed Phase 4
~12670

Find a Location

Who is running the clinical trial?

Biohaven Pharmaceuticals, Inc.Lead Sponsor
47 Previous Clinical Trials
37,048 Total Patients Enrolled
Biohaven Pharmaceutical Holding Company Ltd.Industry Sponsor
8 Previous Clinical Trials
13,990 Total Patients Enrolled
PfizerLead Sponsor
4,567 Previous Clinical Trials
10,911,787 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Are new participants being recruited for this experiment?

"The latest information on clinicaltrials.gov shows that this trial is still looking for participants. The initial posting was on May 5th, 2022 and the page was updated as recently as October 14th, 2022."

Answered by AI

Is this study prominent in Canada?

"17 medical facilities are participating in this clinical trial, these include Red Star Research in Lake Jackson, University of Pittsburgh in Pittsburgh and North Suffolk Neurology in Commack. There are also 14 other locations."

Answered by AI

How many people are allowed to participate in this clinical trial at any one time?

"The sponsor, Biohaven Pharmaceutical Holding Company Ltd., needs to enrol 200 eligible patients from various locations including Red Star Research in Lake Jackson, Texas and University of Pittsburgh in Pittsburgh, New york."

Answered by AI

Who else is applying?

What state do they live in?
Georgia
How old are they?
18 - 65
What site did they apply to?
ForCare Clinical Research
What portion of applicants met pre-screening criteria?
Met criteria
Recent research and studies
clinicaltrials.govStudy
Safety and Efficacy of BHV-3000 (Rimegepant) Orally Disintegrating Tablet for Acute Treatment of Temporomandibular Disorders
2022. "Safety and Efficacy of BHV-3000 (Rimegepant) Orally Disintegrating Tablet for Acute Treatment of Temporomandibular Disorders". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05262517.
~30 spots leftby Apr 2025
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