← Back to Search

Behavioral Intervention

Common Elements Toolbox (COMET) for Depression (COMET-Prol Trial)

N/A
Waitlist Available
Research Sponsored by Indiana University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
A positive response (i.e., "yes") to the question: "Do you have or have you had a diagnosed, ongoing mental health/illness/condition?"
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 8 weeks
Awards & highlights

COMET-Prol Trial Summary

This trial will test a digital mental health intervention against a control group to see if it is effective. The intervention includes modules on cognitive restructuring, gratitude, behavioral activation, and self-compassion.

Eligible Conditions
  • Depression
  • Anxiety
  • Emotion Regulation

COMET-Prol Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

COMET-Prol Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~8 weeks
This trial's timeline: 3 weeks for screening, Varies for treatment, and 8 weeks for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
2-week change in the Generalized Anxiety Disorder 7 scale (GAD7)
2-week change in the Patient Health Questionnaire
8-week change in the Generalized Anxiety Disorder 7 scale (GAD7) 8-week change in the Generalized Anxiety Disorder 7 scale (GAD7)
+1 more
Secondary outcome measures
8-week change in Emotion Regulation Scale (ERQ) - Reappraisal subscale
8-week change in the Emotion Regulation Scale (ERQ) - Suppression subscale
8-week change in the Work and Social Adjustment Scale (WSAS)
+1 more

COMET-Prol Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: Common Elements Toolbox (COMET)Experimental Treatment1 Intervention
COMET consists of the following modules: cognitive restructuring (labeled "flexible thinking"), behavioral activation (labeled "positive activities"), gratitude, and self-compassion. Participants complete these COMET modules by themselves. The format is reading psychoeducational along with completing specific activities.
Group II: Waiting list control (WLC)Active Control1 Intervention
Participants who are assigned to the control condition will complete the baseline questionnaires and assessments at weeks 2, 4, and 8. After the last assessment, they will be given access to COMET.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Common Elements Toolbox (COMET)
2022
N/A
~830

Find a Location

Who is running the clinical trial?

Indiana UniversityLead Sponsor
980 Previous Clinical Trials
982,153 Total Patients Enrolled
28 Trials studying Depression
10,102 Patients Enrolled for Depression

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Who else is applying?

What state do they live in?
Alabama
How old are they?
18 - 65
What site did they apply to?
Indiana University
What portion of applicants met pre-screening criteria?
Met criteria
Recent research and studies
clinicaltrials.govStudy
Efficacy of COMET on Prolific Participants
Lorenzo Lorenzo-Luaces 2022. "Efficacy of COMET on Prolific Participants". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT05379881.
~301 spots leftby Apr 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top