← Back to Search

Other

Bupropion Hydrochloride, Naltrexone Hydrochoride Drug Combination for Binge Eating Disorder

Phase 2 & 3
Waitlist Available
Led By Carlos M Grilo, PhD
Research Sponsored by Yale University
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 12 months post-treatment
Awards & highlights

Study Summary

This trial will test if a certain combination of drugs is effective in treating patients with binge-eating disorder, with or without obesity.

Eligible Conditions
  • Binge Eating Disorder

Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~12 months post-treatment
This trial's timeline: 3 weeks for screening, Varies for treatment, and 12 months post-treatment for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Percent BMI Change
Secondary outcome measures
Body Mass Index
Change in Binge Eating Frequency

Side effects data

From 2023 Phase 2 & 3 trial • 89 Patients • NCT03539900
33%
Dry Mouth
23%
Constipation
16%
Dizziness
14%
Nausea
7%
Vomiting
7%
Anxiety
5%
Insomnia
5%
Headache
2%
Diarrhea
100%
80%
60%
40%
20%
0%
Study treatment Arm
NB Medication
Placebo

Trial Design

2Treatment groups
Experimental Treatment
Placebo Group
Group I: NB MedicationExperimental Treatment1 Intervention
Bupropion Hydrochloride, Naltrexone Hydrochoride Drug Combination
Group II: PlaceboPlacebo Group1 Intervention
Placebo will be inactive and taken daily in pill form.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Bupropion Hydrochloride, Naltrexone Hydrochoride Drug Combination
2018
Completed Phase 3
~90

Find a Location

Who is running the clinical trial?

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)NIH
2,359 Previous Clinical Trials
4,315,406 Total Patients Enrolled
Yale UniversityLead Sponsor
1,851 Previous Clinical Trials
2,738,124 Total Patients Enrolled
Carlos M Grilo, PhDPrincipal InvestigatorYale School of Medicine
4 Previous Clinical Trials
369 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

How many people are signing up to participate in this clinical trial?

"No, this study is not recruiting at the moment. The clinical trial was initially posted on 4/17/2018 and was last edited on 2/18/2022. There are presently 108 studies actively looking for participants with binge-eating disorder and 71 trials for Bupropion Hydrochloride, Naltrexone Hydrochoride Drug Combination actively recruiting patients if you are exploring for other studies."

Answered by AI

Is this study's target demographic 20 years or older?

"Enrolment in this trial is restricted to patients aged 18-70. There are 49 other clinical trials for people below the age of 18 and 108 for those over 65."

Answered by AI

Are people currently being signed up for this research project?

"This particular trial is not currently looking for patients, however it was last updated on February 18th, 2022. There are a total of 179 other clinical trials that you may be eligible for."

Answered by AI

Who would be a suitable candidate for enrolling in this research project?

"200 individuals between the ages of 18 and 70 who currently suffer from binge-eating disorder are being enrolled in this study. Furthermore, it is a requirement that participants also meet the following obesity (BMI >30 and <50) or non-obesity (BMI >21.5 and <29.9) range;, Available for the duration of the treatment and follow-up (15 months); criteria."

Answered by AI

What does Bupropion Hydrochloride, Naltrexone Hydrochoride Drug Combination help patients with?

"Bupropion Hydrochloride in combination with Naltrexone Hydrochoride can be used to effectively treat patients with attention deficit hyperactivity disorder (ADHD), seasonal affective disorder, and those looking to quit smoking cigarettes."

Answered by AI

Who else is applying?

What state do they live in?
Vermont
How old are they?
18 - 65
What site did they apply to?
Yale School of Medicine
What portion of applicants met pre-screening criteria?
Met criteria
Recent research and studies
clinicaltrials.govStudy
Efficacy and Mechanisms of Naltrexone+Bupropion for Binge Eating Disorder
2018. "Efficacy and Mechanisms of Naltrexone+Bupropion for Binge Eating Disorder". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03539900.
~13 spots leftby Apr 2025
Unbiased ResultsWe believe in providing patients with all the options.
Your Data Stays Your DataWe only share your information with the clinical trials you're trying to access.
Verified Trials OnlyAll of our trials are run by licensed doctors, researchers, and healthcare companies.
Back to top