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Oxytocin for Smoking (MOXY Trial)

Phase 2 & 3
Waitlist Available
Research Sponsored by University of Southern California
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Smoke at least 10 cigarettes per day for the past year
Be between 18 and 65 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up throughout study completion, an average of two weeks.
Awards & highlights

MOXY Trial Summary

This trial is testing if mindfulness training + oxytocin nasal spray can help people quit smoking.

Eligible Conditions
  • Smoking
  • Smoking Cessation

MOXY Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below

MOXY Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~throughout study completion, an average of two weeks.
This trial's timeline: 3 weeks for screening, Varies for treatment, and throughout study completion, an average of two weeks. for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Smoking Lapse Analogue Task (delay score)
Trier Social Stress Test
Secondary outcome measures
Diastolic blood pressure
Heart rate
Systolic blood pressure

MOXY Trial Design

3Treatment groups
Experimental Treatment
Active Control
Placebo Group
Group I: Mindfulness and intranasal oxytocinExperimental Treatment2 Interventions
Given oxytocin through intranasal administration and self-directed mindfulness training.
Group II: Mindfulness and placeboActive Control2 Interventions
Given sterile saline through intranasal adminstration and self-directed mindfulness training.
Group III: Sham mindfulness and placeboPlacebo Group2 Interventions
Given sterile saline through intranasal adminstration and sham self-directed mindfulness training.
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Oxytocin
FDA approved
Mindfulness
2014
Completed Phase 3
~2670

Find a Location

Who is running the clinical trial?

University of Southern CaliforniaLead Sponsor
906 Previous Clinical Trials
1,596,108 Total Patients Enrolled
1 Trials studying Smoking
212 Patients Enrolled for Smoking
MGM FoundationUNKNOWN

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Who else is applying?

What state do they live in?
California
How old are they?
18 - 65
What site did they apply to?
University of Southern California
What portion of applicants met pre-screening criteria?
Met criteria

How responsive is this trial?

Typically responds via
Email
Recent research and studies
clinicaltrials.govStudy
Mindfulness Training Plus Oxytocin
David Black 2018. "Mindfulness Training Plus Oxytocin". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03819231.
~28 spots leftby Apr 2025
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