← Back to Search

Hormone Therapy

Somatropin for Burns

Phase 2 & 3

Waitlist Available

Led By Ludwik K Branski, MD, MMS

Research Sponsored by The University of Texas Medical Branch, Galveston

Eligibility Criteria Checklist

Specific guidelines that determine who can or cannot participate in a clinical trial

Must have

Be older than 18 years old

Timeline

Screening 3 weeks

Treatment Varies

Follow Up 24 months post burn-injury

Awards & highlights

Study Summary

This trial is testing whether growth hormone can help prevent height, weight, and muscle loss in burn patients.

Eligible Conditions

Burns
Growth Hormone Therapy

Timeline

Screening ~ 3 weeks3 visits

Treatment ~ Varies

Follow Up ~ 24 months post burn-injury

Screening ~ 3 weeks

Treatment ~ Varies

Follow Up ~24 months post burn-injury

This trial's timeline: 3 weeks for screening, Varies for treatment, and 24 months post burn-injury for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.

Primary outcome measures

Lean body mass

Secondary outcome measures

Change in FEV1/FVC ratio expressed as a percentage (FEV1/FVC%)

Change in Forced vital capacity (FVC)

Oxygen

+30 more

Side effects data

From 2017 Phase 4 trial • 82 Patients • NCT02311894

21%

Headache

15%

Vomiting

10%

Upper respiratory tract infection

Injection site bruising

Rash

Pharyngitis streptococcal

Nasopharyngitis

Pyrexia

100%

80%

60%

40%

20%

Study treatment Arm

Somatropin

Trial Design

2Treatment groups

Experimental Treatment

Placebo Group

Group I: Growth HormoneExperimental Treatment1 Intervention

Daily subcutaneous injections of 0.05 mg/kg/day of Growth Hormone [somatropin, Genotropin, Pfizer, New York, NY] will be administered, from one week prior to discharge until 9 months post-burn.

Group II: 0.09% saline solutionPlacebo Group1 Intervention

Daily subcutaneous injections of 0.09% of saline solution will be administered, from one week prior to discharge until 9 months post-burn.

Treatment

First Studied

Drug Approval Stage

How many patients have taken this drug

Somatropin

2015

Completed Phase 4

~67770

Do I qualify?Apply below to find out

Find a Location

Who is running the clinical trial?

The University of Texas Medical Branch, GalvestonLead Sponsor

243 Previous Clinical Trials

56,658 Total Patients Enrolled

28 Trials studying Burns

13,311 Patients Enrolled for Burns

United States Department of DefenseFED

864 Previous Clinical Trials

327,586 Total Patients Enrolled

17 Trials studying Burns

1,510 Patients Enrolled for Burns

PfizerIndustry Sponsor

4,570 Previous Clinical Trials

10,915,972 Total Patients Enrolled

1 Trials studying Burns

16 Patients Enrolled for Burns

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

For what conditions is Somatropin typically prescribed?

"Somatropin is the most popular medication for general surgery, but it can also have benefits for treating other conditions such as short stature, open epiphyses, and antiretroviral therapy."

Answered by AI

Could I potentially qualify to be a participant in this research?

"The study is enrolling 64 individuals that have sustained burns and are aged between 18 and 85. The key inclusion criteria are as follows: being within the specified age range and having more than 30% of their total body surface area affected by burns."

Answered by AI

Are new volunteers being taken for this research project?

"According to the latest update on clinicaltrials.gov, this trial is no longer recruiting patients. The study was first posted on November 1st, 2015 but has not been updated since May 3rd, 2022. There are, however, 119 other trials that are presently looking for participants."

Answered by AI

Are people aged 40+ being recruited for this trial?

"In order to participate in this trial, applicants must between 18 and 85 years old. There are currently 43 trials underway for people under the age of 18 and 75 for patients over 65."

Answered by AI

Has Somatropin been used before in other medical research trials?

"There are currently 35 active clinical trials observing the effects of Somatropin, 14 of which are in Phase 3. Most of these trials are based in Philadelphia, Pennsylvania, but Somatropin is being studied in 646 locations globally."

Answered by AI

Recent research and studies

Pediatric Clinics of North AmericaJournal

Pediatric Trauma: Prevention Strategies

Stylianos, Steven, and Martin R. Eichelberger. 1993. “Pediatric Trauma: Prevention Strategies”. Pediatric Clinics of North America. Elsevier BV. doi:10.1016/s0031-3955(16)38666-7.

clinicaltrials.govStudy

Growth Hormone Therapy for Muscle Regeneration in Severely Burned Patients

2015. "Growth Hormone Therapy for Muscle Regeneration in Severely Burned Patients". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03038594.