60 Participants NeededMy employer runs this trial

LY4005130 for Hair Loss

Recruiting at 28 trial locations
Tq
Pi
Overseen ByPhysicians interested in becoming principal investigators please contact
Prior Safety DataThis treatment has passed at least one previous human trial

What You Need to Know Before You Apply

What is the purpose of this trial?

The purpose of this study is to evaluate how well LY4005130 works in participants with severe alopecia areata (hair loss) when compared with placebo, and how well it's tolerated and what side effects may occur. Blood tests will be performed to investigate how the body processes the study drug and how the study drug affects the body.

The study drug will be administered intravenously (IV) (into a vein in the arm).

The study will last approximately 48 weeks, including screening.

Who Is on the Research Team?

C1

Call 1-877-CTLILLY (1-877-285-4559) or 1-317-615-4559 Mon - Fri 8 AM - 8 PM Eastern time (UTC/GMT - 5 hours, EST)

Principal Investigator

Eli Lilly and Company

Are You a Good Fit for This Trial?

Inclusion Criteria

No significant spontaneous hair regrowth in the investigator's opinion for at least 6 months
Agree not to use any AA treatments during the study
I have severe hair loss covering 50% to 90% of my scalp from Alopecia Areata.
See 1 more

Exclusion Criteria

My hair loss is mostly diffuse, with widespread shedding.
I do not have any serious or unstable health conditions affecting major organs.
I currently have another type of hair loss.
See 3 more

Timeline for a Trial Participant

Screening

Participants are screened for eligibility to participate in the trial

2-4 weeks

Treatment

Participants receive LY4005130 or placebo intravenously to evaluate efficacy and safety

24 weeks
Regular visits for IV administration and monitoring

Follow-up

Participants are monitored for safety and effectiveness after treatment

20-22 weeks

What Are the Treatments Tested in This Trial?

Interventions

  • LY4005130

How Is the Trial Designed?

2

Treatment groups

Experimental Treatment

Placebo Group

Group I: LY4005130Experimental Treatment1 Intervention
Group II: PlaceboPlacebo Group1 Intervention

Find a Clinic Near You

Who Is Running the Clinical Trial?

Eli Lilly and Company

Lead Sponsor

Trials
2,708
Recruited
3,720,000+
Dr. Daniel Skovronsky profile image

Dr. Daniel Skovronsky

Eli Lilly and Company

Chief Medical Officer since 2018

MD from Harvard Medical School

David A. Ricks profile image

David A. Ricks

Eli Lilly and Company

Chief Executive Officer since 2017

BSc from Purdue University, MBA from Indiana University