Your session is about to expire
← Back to Search
Exercise for Brain Health in Older African Americans
Phase 2
Waitlist Available
Led By Mark A. Gluck, PhD
Research Sponsored by Rutgers, The State University of New Jersey
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial Must have
Be age 60 or older
Independently ambulatory (i.e., not needing a wheelchair, walker, or cane)
Timeline
Screening 3 weeks
Treatment Varies
Follow Up changes from baseline to six months
Awards & highlights
Study Summary
This trial will test if exercise can reduce Alzheimer's risk by improving cognitive and brain health in older African Americans.
Who is the study for?
This trial is for African Americans aged 60 or older who are physically able to participate, speak English, and have low physical activity levels. They must be cleared by their doctor, not use mobility aids, and score within certain ranges on cognitive tests. People with color-blindness, neurological disorders, major psychiatric conditions, recent substance abuse treatment or plans for surgery can't join.Check my eligibility
What is being tested?
The study compares the impact of Cardio-Dance Fitness (CDF) versus Strength, Flexibility & Balance (SFB) exercises on brain health markers related to Alzheimer's risk in older African Americans. It includes health assessments, cognitive tests, fMRI scans and blood tests before and after the interventions.See study design
What are the potential side effects?
While specific side effects aren't listed for exercise interventions like CDF or SFB programs in this context; generally possible side effects may include muscle soreness or strain from new physical activities.
Eligibility Criteria
Inclusion Criteria
You may be eligible if you check “Yes” for the criteria belowSelect...
I am 60 years old or older.
Select...
I can walk without any help from devices like wheelchairs or canes.
Timeline
Screening ~ 3 weeks3 visits
Treatment ~ Varies
Follow Up ~ changes from baseline to six months
Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~changes from baseline to six months
Treatment Details
Study Objectives
Outcome measures can provide a clearer picture of what you can expect from a treatment.Primary outcome measures
Generalization Performance on the Acquired Equivalence Task
Generalization Performance on the Concurrent Discrimination and Transfer Task
Neurons
Other outcome measures
Exploratory Outcome: AB 42/40
Neurofilaments
Exploratory Outcome: p-tau181
+1 moreTrial Design
2Treatment groups
Experimental Treatment
Active Control
Group I: Cardio-Dance FitnessExperimental Treatment1 Intervention
This is the experimental group. Participants will meet three times a week for dance classes for approximately 60 minutes per session, over 24 weeks (approximately 6 months).
Group II: Strength, Flexibility & BalanceActive Control1 Intervention
This is the active control group. Participants will meet three times a week for strength, flexibility, and balance exercises for approximately 60 minutes per session, over 24 weeks (approximately 6 months).
Who is running the clinical trial?
Rutgers, The State University of New JerseyLead Sponsor
429 Previous Clinical Trials
63,952 Total Patients Enrolled
Göteborg UniversityOTHER
417 Previous Clinical Trials
910,565 Total Patients Enrolled
University of California, IrvineOTHER
542 Previous Clinical Trials
1,921,721 Total Patients Enrolled
Media Library
Eligibility Criteria:
This trial includes the following eligibility criteria:- I am 60 years old or older.I can walk without any help from devices like wheelchairs or canes.You cannot see certain colors, which may affect your ability to complete some tasks in the study.I have a diagnosed neurological disorder.I do not have major mental health issues, substance abuse history, or recent cancer treatments that could affect the study.I don't have recent severe heart issues or uncontrolled high blood pressure.You do not meet the criteria for being physically active, which means you do not exercise for at least 60 minutes per week.You score between 28 and 35 on a test that checks how well you can think and remember things over the phone.You scored between 20 and 26 on the Montreal Cognitive Assessment (MoCA) during the in-person screening.
Research Study Groups:
This trial has the following groups:- Group 1: Cardio-Dance Fitness
- Group 2: Strength, Flexibility & Balance
Awards:
This trial has 1 awards, including:- No Placebo-Only Group - All patients enrolled in this study will receive some form of active treatment.
Timeline:
This trial has the following timeline:- Screening: It may take up to 3 Weeks to process to see if you qualify in this trial.
- Treatment: The duration you will receive the treatment varies.
- Follow Ups: You may be asked to continue sharing information regarding the trial for 6 Months after you stop receiving the treatment.
Frequently Asked Questions
These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.
Can Cardio-Dance Fitness be detrimental to a patient's health?
"The safety of Cardio-Dance Fitness has been estimated to be a 2 on the 1 to 3 scale due to its Phase 2 testing. This suggests that there is some data supporting safety, but none supporting efficacy."
Answered by AI
Are there any remaining opportunities to partake in this research initiative?
"Information on clinicaltrials.gov informs us that this medical trial, which was initially posted in March of 2023, is not actively recruiting new patients at the moment. Despite this fact, 863 other trials are currently enlisting individuals as we speak."
Answered by AI
Other Trials to Consider
Popular Categories
Share this study with friends
Copy Link
Messenger