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Neurocognitive Empowerment for Addiction Treatment (NEAT) for Opioid Use Disorder (NEAT Trial)

N/A
Waitlist Available
Research Sponsored by Laureate Institute for Brain Research, Inc.
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Be older than 18 years old
Timeline
Screening 3 weeks
Treatment Varies
Follow Up from pre to post intervention (4 weeks following last intervention session, on average at 18 weeks after baseline assessment)
Awards & highlights

NEAT Trial Summary

This trial will test the efficacy of a new program, NEAT, designed to help people with substance abuse disorders recover by targeting neurocognitive deficits. The program will be compared to a control intervention, and participants will be followed for 12 months to see if the program helps with long-term recovery.

Eligible Conditions
  • Opioid Use Disorder
  • Amphetamine Use Disorder

NEAT Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~from pre to post intervention (4 weeks following last intervention session, on average at 18 weeks after baseline assessment)
This trial's timeline: 3 weeks for screening, Varies for treatment, and from pre to post intervention (4 weeks following last intervention session, on average at 18 weeks after baseline assessment) for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Change in craving self-report measured with Obsessive Compulsive Drug Use Scale (OCDUS) total score
Secondary outcome measures
Change in cognitive concerns self-report as measured by the Patient Reported Outcomes Measurement Information System (PROMIS) Cognitive Concerns
Other outcome measures
Change in anger as measured by the Patient Reported Outcomes Measurement Information System (PROMIS) Anger
Change in cortical-subcortical connectivity in resting state fMRI
Change in cortical-subcortical task-based connectivity in cue exposure fMRI
+18 more

NEAT Trial Design

2Treatment groups
Experimental Treatment
Active Control
Group I: NEAT Active Experimental GroupExperimental Treatment1 Intervention
People in the active group will receive NEAT intervention
Group II: Control GroupActive Control1 Intervention
People in the control group will receive non-essential regularly-scheduled programming (active control) coinciding with the same timeframe
Treatment
First Studied
Drug Approval Stage
How many patients have taken this drug
Neurocognitive Empowerment for Addiction Treatment (NEAT)
2019
N/A
~110

Find a Location

Who is running the clinical trial?

Laureate Institute for Brain Research, Inc.Lead Sponsor
50 Previous Clinical Trials
5,241 Total Patients Enrolled
Oklahoma Center for the Advancement of Science and TechnologyOTHER
6 Previous Clinical Trials
520 Total Patients Enrolled

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Who would be an appropriate candidate for this research project?

"The prerequisites for this study are that patients must have a history of opioid abuse and be between 18 to 65 years old. A total of 80 individuals will be allowed into the trial."

Answered by AI

Are patients still being enrolled in this research project?

"That is correct, according to the clinicaltrials.gov listing, this trial is looking for enrollees. This research was initially made public on March 6th, 2019 and was updated most recently on April 4th, 2022. The aim is to have 80 people take part in this study at a single location."

Answered by AI

Does this research project restrict participants to a certain age group?

"According to the inclusion criteria listed on this trial, patients that enroll must be aged 18 to 65. There are a total of 345 studies for people under 18 and 975 for patients older than 65."

Answered by AI

How many test subjects are included in this experiment?

"That is correct. Based on the information provided by clinicaltrials.gov, this study is still in need of patients. The trial was originally posted on March 6th, 2019 and has since been edited April 4th, 2022. They are looking for a total of 80 participants at 1 location."

Answered by AI

Who else is applying?

What state do they live in?
Arkansas
Oklahoma
California
How old are they?
18 - 65
What site did they apply to?
Laureate Institute for Brain Research
What portion of applicants met pre-screening criteria?
Met criteria
How many prior treatments have patients received?
2

Why did patients apply to this trial?

Ive tried other treatments that did not work.
PatientReceived 1 prior treatment

How responsive is this trial?

Typically responds via
Email
Most responsive sites:
  1. Laureate Institute for Brain Research: < 48 hours
Average response time
  • < 2 Days
Recent research and studies
TrialsJournal
Neurocognitive Empowerment for Addiction Treatment (NEAT): Study Protocol for a Randomized Controlled Trial
Ekhtiari, Hamed, Tara Rezapour, Brionne Sawyer, Hung-Wen Yeh, Rayus Kuplicki, Mimi Tarrasch, Martin P Paulus, and Robin Aupperle. 2021. “Neurocognitive Empowerment for Addiction Treatment (NEAT): Study Protocol for a Randomized Controlled Trial”. Trials. Springer Science and Business Media LLC. doi:10.1186/s13063-021-05268-8.
clinicaltrials.govStudy
Neurocognitive Empowerment for Addiction Treatment (NEAT) in Opioid Use Disorder and Amphetamine Use Disorder
2019. "Neurocognitive Empowerment for Addiction Treatment (NEAT) in Opioid Use Disorder and Amphetamine Use Disorder". ClinicalTrials.gov. https://clinicaltrials.gov/ct2/show/NCT03922646.
~17 spots leftby Apr 2025
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