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Low-Dose High-Resolution Breast CT for Breast Cancer (LowerDoseBCT Trial)

N/A
Waitlist Available
Led By Srinivasan Vedantham, PhD
Research Sponsored by University of Arizona
Eligibility Criteria Checklist
Specific guidelines that determine who can or cannot participate in a clinical trial
Must have
Patients who satisfy University of Arizona (UA) - Banner University Medical Center (BUMC), Department of Medical Imaging policy for administration of iodinated contrast media for computed tomography (CT) imaging, which may include a blood draw for renal function assessment.
Patients who were asymptomatic and 40 years of age or older (typical screening age range) at the time of the screening exam that prompted the recall
Timeline
Screening 3 weeks
Treatment Varies
Follow Up 18 months
Awards & highlights

LowerDoseBCT Trial Summary

This trial is testing a new breast imaging technique to see if it can better distinguish between cancerous and non-cancerous growths.

Who is the study for?
This trial is for women over 40 who've had a suspicious breast screening result (BI-RADS category 4 or 5) and no known allergies to iodinated contrast media. It's not for those unable to consent, with physical limitations, over the BCT table weight limit of 440 lbs, prior thorax radiation treatment, impaired kidney function, history of excessive diagnostic x-rays, men, under age 40, prisoners or pregnant/breastfeeding women.Check my eligibility
What is being tested?
The study tests if a new type of breast imaging called dedicated breast CT (BCT) can better reveal small structures in the breast tissue and improve accuracy in diagnosing breast cancer compared to traditional methods like mammography.See study design
What are the potential side effects?
Potential side effects may include reactions to iodinated contrast media used during BCT such as nausea or itching. There might also be discomfort from lying prone on the exam table and exposure to additional radiation.

LowerDoseBCT Trial Eligibility Criteria

Inclusion Criteria

You may be eligible if you check “Yes” for the criteria below
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I meet the requirements for CT scans with contrast at UA-BUMC.
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I was 40 or older and had no symptoms when my screening led to further tests.

LowerDoseBCT Trial Timeline

Screening ~ 3 weeks
Treatment ~ Varies
Follow Up ~18 months
This trial's timeline: 3 weeks for screening, Varies for treatment, and 18 months for reporting.

Treatment Details

Study Objectives

Outcome measures can provide a clearer picture of what you can expect from a treatment.
Primary outcome measures
Diagnostic accuracy
Secondary outcome measures
Contrast enhancement quantification

LowerDoseBCT Trial Design

1Treatment groups
Experimental Treatment
Group I: Dedicated breast computed tomography (BCT)Experimental Treatment1 Intervention
All subjects will undergo bilateral breast CT (BCT) imaging exam.

Find a Location

Who is running the clinical trial?

University of ArizonaLead Sponsor
512 Previous Clinical Trials
147,633 Total Patients Enrolled
22 Trials studying Breast Cancer
1,964 Patients Enrolled for Breast Cancer
National Institutes of Health (NIH)NIH
2,682 Previous Clinical Trials
6,930,198 Total Patients Enrolled
49 Trials studying Breast Cancer
110,185 Patients Enrolled for Breast Cancer
National Cancer Institute (NCI)NIH
13,621 Previous Clinical Trials
40,926,822 Total Patients Enrolled
938 Trials studying Breast Cancer
1,542,743 Patients Enrolled for Breast Cancer

Media Library

Contrast-media enhanced breast CT(CE-BCT) Clinical Trial Eligibility Overview. Trial Name: NCT03954431 — N/A
Breast Cancer Research Study Groups: Dedicated breast computed tomography (BCT)
Breast Cancer Clinical Trial 2023: Contrast-media enhanced breast CT(CE-BCT) Highlights & Side Effects. Trial Name: NCT03954431 — N/A
Contrast-media enhanced breast CT(CE-BCT) 2023 Treatment Timeline for Medical Study. Trial Name: NCT03954431 — N/A

Frequently Asked Questions

These questions and answers are submitted by anonymous patients, and have not been verified by our internal team.

Is it currently possible to enroll in this research effort?

"According to the information hosted on clinicaltrials.gov, this particular medical trial is not accepting patients at present; it was initially posted on December 1st 2022 and last updated November 4th 2022. Nonetheless, there are many other trials actively recruiting individuals - 1403 in total!"

Answered by AI
~400 spots leftby Dec 2026